性类固醇对骨矿物质密度和形态影响的研究进展

Q4 Medicine

中华内分泌代谢杂志 Pub Date : 2019-11-25 DOI:10.3760/CMA.J.ISSN.1000-6699.2019.11.012

Rui Zhang

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引用次数: 0

摘要

性类固醇在骨骼的生长、发育和维护中起着重要作用。骨量生长存在性别差异。年轻男性的骨骼结构和强度比年轻女性更强，这是充分利用含有雄激素的睾酮、其芳构化及其还原产物的结果。随着男性和女性年龄的增长，男性的骨量减少发生得比女性晚，这是男性雌激素适度减少的结果。我们的综述是基于几种临床病理模型总结男性和女性骨代谢差异的影响，并回顾该领域的最新研究。关键词：性类固醇；骨密度；骨形态

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Progress in the effects of sex steroids on bone mineral density and morphology

Sex steroids play an important role in the growth, development, and maintenance of the bone. Sex differences are observed in bone mass growth. Bone structure and strength in young males are stronger than young females, which are results of the fully utilization of androgen containing testosterone, its aromatization and its reduction products. As male and female growing older, the reduction in bone mass of males happens later than that of females, which are result of the more moderate decrease of estrogen in males. Our review is to summarize the effects of bone metabolism differences between males and females based on several clinical pathological models and to review the latest researches in this field. Key words: Sex steroid; Bone mineral density; Bone morphology

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来源期刊

中华内分泌代谢杂志 Medicine-Endocrinology, Diabetes and Metabolism

CiteScore

0.60

自引率

0.00%

发文量

7243

期刊介绍： The Chinese Journal of Endocrinology and Metabolism was founded in July 1985. It is a senior academic journal in the field of endocrinology and metabolism sponsored by the Chinese Medical Association. The journal aims to be the "Chinese broadcaster of new knowledge on endocrinology and metabolism worldwide". It reports leading scientific research results and clinical diagnosis and treatment experience in endocrinology and metabolism and related fields, as well as basic theoretical research that has a guiding role in endocrinology and metabolism clinics and is closely integrated with clinics. The journal is a core journal of Chinese science and technology (a statistical source journal of Chinese science and technology papers), and is included in Chinese and foreign statistical source journal databases such as the Chinese Science and Technology Papers and Citation Database, Chemical Abstracts, and Scopus.