心碎的研究:马来西亚takotsubo心肌病的实用病例报告

Q4 Medicine
Syeda Humayra, Abd. Rahim Mohamad, A. Ghapar, L. Mohamed
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引用次数: 0

摘要

Takotsubo综合征是一种获得性、非缺血性应激诱导的心肌病,通常被称为“心碎综合征”。这是一种急性左心室功能障碍,主要发生在老年女性的强烈压力事件后。确切的病理生理学仍然难以捉摸。这个词于20世纪90年代初在日本出现,在日本,左心室形状的独特变化伴随着收缩期心尖气球的膨胀,类似于日本渔民使用的章鱼锅Takotsubo。从一种罕见的被低估的综合征,它越来越被认为是急性心力衰竭的一种形式。该综合征的临床诊断可能无法确定,因为它与急性冠状动脉综合征相似,但在血管造影成像中没有冠状动脉狭窄。心脏生物标志物、肌钙蛋白和钠尿肽显著升高,有助于区分Takotsubo综合征和心肌梗死。本文报告一位59岁的马来西亚妇女,她患有典型的复发性Takotsubo综合征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE STUDY OF BROKEN HEARTS: A PRAGMATIC CASE REPORT ON TAKOTSUBO CARDIOMYOPATHY IN MALAYSIA
The Takotsubo syndrome is an acquired, non-ischemic stress-induced cardiomyopathy popularly known as the ‘broken heart syndrome’. It is an acute left ventricular dysfunction presenting mostly in older women after an intensely stressful event. The exact pathophysiology remains elusive. The term came into existence in the early 1990s in Japan, where the distinctive change in the shape of the left ventricle with apical ballooning during systole, resembled the Takotsubo, an octopus pot used bythe Japanese fisherman. From a rare underrecognized syndrome, it has been increasingly recognised as a form of acute cardiac failure. Clinical diagnosis of the syndrome may be unidentified due to its similarity with the acute coronary syndrome, but without the narrowing of coronary vessels in angiographic imaging. There is a substantial elevation of the cardiac biomarkers, troponin and the natriuretic peptides which helps in differentiating the Takotsubo syndrome from myocardial infarction. A case report of a 59-year old Malaysian lady with typical, recurrent episodes of the Takotsubo syndrome is presented.
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