类人猿的基因组变异及其在保护中的应用

T. Marques-Bonet, C. Hvilsom
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引用次数: 4

摘要

类人猿都面临着在本世纪内灭绝的威胁。因此,为了深入了解我们最亲近的亲戚的基因动力学,并帮助找到避免它们灭绝的方法,需要创新的保护遗传学努力。最近,新技术使得利用全基因组序列成为可能,我们现在可以在群体规模上获得全基因组变异,这将导致保护遗传学的新应用。本文将对近5年来类人猿基因组变异研究的主要成果进行综述,并对当前和未来类人猿基因组变异研究的进展进行展望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Genomic variation of the great apes and the application to conservation

Genomic variation of the great apes and the application to conservation

The great apes all share the same fate of being threatened by extinction within the present century. Therefore innovative conservation genetics efforts are needed in order to gain in-depth knowledge about the gene dynamics of our closest living relatives, and to help find ways to avoid their extinction. Recently, novel technologies have made it possible to exploit whole genome sequences and we now have access to full genome variation at the population scale, which should result in novel applications for conservation genetics. In this review, some of the main findings from the last 5 years of intense research on great ape genomic variation will be summarized, and current and future endeavours to apply this knowledge to assist global great ape conservation efforts will be discussed.

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