强脉冲光治疗深色皮肤型黄褐斑的疗效和安全性评价

Serbian Journal of Dermatology and Venereology Pub Date : 2020-03-01 DOI:10.2478/sjdv-2020-0001

N. Choudhary, Abhishek De, A. Sil, G. Chatterjee

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引用次数: 2

摘要

摘要简介。我们进行了一项前瞻性介入研究，以评估强脉冲光（IPL）治疗深色皮肤表型黄褐斑的疗效和安全性。材料和方法。该研究在32名IV型和V型皮肤患者中进行。使用了640 nm和690 nm滤镜的强脉冲光。患者每月接受一次治疗，共6次。使用黄褐斑面积和严重程度指数（MASI）和临床医生整体印象评分进行评估。我们遵循“按方案”分析。后果在完成治疗的26名患者中，12名患者病情好转，10名患者MASI保持不变，4名患者病情恶化。治疗前后MASI评分分别为6.70±3.53和6.32±3.90（p值=0.6891）。红斑和疼痛是常见的副作用。32名患者中有17名患有甲状腺疾病。结论应避免将强脉冲光作为深色皮肤类型的一线治疗。然而，在某些情况下，经过仔细考虑，它可以用作辅助治疗。

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Evaluation of Efficacy and Safety Profile of Intense Pulsed Light Treatment in Melasma in Darker Skin Type

Abstract Introduction. We undertook a prospective, interventional study to evaluate the efficacy and safety profile of Intense Pulsed light (IPL) treatment of melasma in dark skin phenotypes. Material and Methods. The study was conducted in 32 patients of skin type IV and V. IPL with 640 nm and 690 nm filters was used. The patients were called once a month to undergo 6 sessions. Melasma area and severity index (MASI) and Clinician Global Impression Scores were used for evaluation. We followed “per protocol” analysis. Results. Out of 26 patients who completed the treatment, 12 patients showed improvement, MASI remained unchanged in 10 patients and 4 patients showed deterioration. MASI scores before and after treatment were 6.70 ± 3.53 and 6.32 ± 3.90 (p value=0.6891). Erythema and pain were the common side effects noted. Seventeen out of 32 patients had thyroid disorders. Conclusion. IPL should be avoided as a first line therapy in darker skin type. However, it can be used as an adjuvant therapy in some cases after careful deliberations.

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来源期刊

Serbian Journal of Dermatology and Venereology

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期刊介绍： Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.