森巴西南部KARITAS医院2017年疟疾患者的临床和血红蛋白谱

A. Johan, Audrey Natalia, William Djauhari, R. Effendi
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引用次数: 1

摘要

疟疾高发地区的疟疾感染不是典型的病理学,通常表现出非特异性症状。西南苏姆巴区是疟疾高发区,年寄生虫发病率(API)为14.48‰,为查明疟疾患者的临床和血红蛋白特征,获取西南苏姆巴区疟疾高发区疟疾临床特征的综合信息。这是一项描述性的横断面研究。数据来自2017年1月1日至12月31日期间在西南萨姆巴区卡里塔斯医院的疟疾患者的医疗记录。纳入标准为疟原虫无性期患者。在吉姆萨染色的厚和薄外周血涂片检查中。排除标准是患有并存疾病的疟疾患者,以及在入院前服用过药物的患者。患者总数为322例,50.6%的受试者年龄≥15岁,59.3%为男性。在322名患者中,133名受试者作为住院患者接受治疗。结果表明,大多数感染是由恶性疟原虫的单一感染引起的。最常见的临床症状是发烧(98.4%),其次是头痛、呕吐、咳嗽和恶心。最常见的身体症状是腋窝温度>37.5°C(87.6%),其次是贫血性结膜炎和肝肿大,这主要发生在儿科患者身上。血红蛋白水平≤10 g/dL的患者人数为129人。79%的贫血患者MCV<80fL。根据印尼卫生部制定的严重疟疾标准,本研究在116名受试者中发现了严重疟疾。研究结果与东努沙登加拉省其他高流行地区的其他现有研究一致。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CLINICAL AND HEMOGLOBIN PROFILE OF MALARIA PATIENTS IN KARITAS HOSPITAL, SOUTHWEST SUMBA, PERIOD OF YEAR 2017
Malaria infections in high endemic areas are not pathognomonic and often show non-specific symptoms. The Southwest Sumba district is a high endemic area of malaria with the annual parasite incidence (API) of 14.48‰. The research conducted in this area was to identify the clinical and hemoglobin profile of malaria patients and to obtain comprehensive information on the clinical characteristics of malaria in a high endemic area of Southwest Sumba district. This is a descriptive cross-sectional study. The data was obtained from the medical record of malaria patients between  January 1 st and December 31 st , 2017 in Karitas Hospital, Southwest Sumba district. Inclusion criteria were patients with asexual stages of Plasmodium spp. on their Giemsa-stained thick and thin peripheral blood smears examination. Exclusion criteria were malaria patients with coexisting diseases and who had taken medication before admitted to the hospital. The total number of patients was 322 patients, 50.6% of the subjects were ≥ 15 years old and 59.3% were male. Among 322  patients, 133 subjects were treated as inpatients. The result shows that most infection was caused by a single infection of P. falciparum.  The most common clinical symptom was fever (98.4%), followed by headache, vomiting, cough, and nausea. The most common physical finding was the axillary temperature of > 37.5 ° C (87.6%) followed by anemic conjunctiva and hepatomegaly, which was mostly found in pediatric patients. The number of patients with hemoglobin level ≤ 10 g/dL was 129. The MCV <80 fL was found in 79% of patients with anemia. Severe malaria was found in 116 subjects in this study according to severe malaria criteria set by the Indonesian Ministry of Health. Study results were consistent with other existing studies from other high endemic areas in East Nusa Tenggara province.
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