在巴西获得肿瘤药物:兼顾发展中国家的创新和可持续性

F. Ades
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引用次数: 7

摘要

巴西是一个非洲大陆的发展中国家,在组织一个有效、普遍和负担得起的公共卫生系统方面面临挑战。在资源有限的情况下,卫生保健的预算分配必须与每个人口的卫生优先事项相一致。巴西人口正在老龄化,癌症新增病例可能在不久的将来稳步增加。为了应对额外的癌症负担,必须积极制定与未来健康需求相匹配的战略。在新药的使用和公共卫生系统的可持续性之间保持平衡是一个复杂的问题。必须评估纳入的决定,同时考虑到药物改善公众健康的能力及其货币影响。这是一场社会讨论,从卫生当局到制药公司、研究人员和民间社会,多个利益相关者都参与了这一过程。本文从监管到药物开发的角度讨论了将药物纳入公共卫生系统的问题,以及改善创新药物获取的战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Access to Oncology Drugs in Brazil: Juggling Innovation and Sustainability in Developing Countries
Brazil is a developing country of continental proportions and faces challenges in organizing an effective, universal, and affordable public health system. In a context of limited resources, the budget allocation to health care must be consistent with the health priorities of each population. The Brazilian population is ageing and the number of new cancer cases is likely to steadily increase in the near future. To deal with the extra cancer burden, strategies to match this future health necessity must be proactively put in place. Keeping the balance between the incorporation of a new drug and the sustainability of the public health system is a complex matter. Decisions for incorporation must be assessed, taking into consideration the ability of the drug to improve the public health in relation to its monetary impact. This is a societal discussion, and multiple stakeholders are involved in this process - from health authorities to pharmaceutical companies, researchers, and civil society. This article discusses the issues of incorporating a drug into the public health system and the strategies to improve access to innovative medicines, from the regulatory to the drug development perspectives.
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