纳米乳剂给药系统研究进展

Q3 Medicine
Niranjan Kaushik, N. Mishra, Pramod Kumar Sharma, M. Alam
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引用次数: 0

摘要

在纳米乳液中,油滴和水滴都由两亲性表面活性剂稳定。具有不同载药量、粘弹性和美学特征的超细分散体可用于给药。已经确定了纳米乳液的20–500纳米液滴尺寸范围。纳米乳液制剂的生物行为在很大程度上受其液滴直径和表面性质的影响。小液滴尺寸可形成透明乳液;因此,即使添加油相,产品的外观也不受影响。纳米乳液是透明或半透明的水包油分散体,通过液滴尺寸小于100nm的表面活性剂和助表面活性剂颗粒的界面层稳定。基于纳米科学的新技术作为改善食品安全、质量和营养的一种手段越来越受欢迎。在该领域,纳米乳液一直是一个关键焦点,因为它们可以很容易地使用当前的食品成分和技术制造。食品纳米乳液是分布在水中的微小油滴,被用作各种疏水性化合物的递送方法,包括营养素、营养品、抗氧化剂和抗菌剂。本文综述了纳米乳液的制备、表征及其应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nano Emulsion Drug Delivery System: A Review
In nanoemulsions, both oil and water droplets are stabilised by an amphiphilic surfactant. Ultrafine dispersions with varying drug loading, viscoelastic properties, and aesthetic characteristics may be useful for the administration of medication. A 20–500-nanometer droplet size range for nanoemulsions has been established. The biological behavior of a nanoemulsions formulation is heavily influenced by its droplet diameter and surface properties. Small droplet size results in clear emulsions; therefore, the appearance of the product is unaffected even by the addition of an oil phase. Nanoemulsions are oil-in-water dispersions that are transparent or translucent and are stabilized by an interfacial layer of surfactants and cosurfactant particles with droplet size smaller than 100 nm. New nanoscience-based technologies are becoming increasingly popular as a means of improving food safety, quality, and nutrition. In this field, nanoemulsions have been a key focus since they can be readily manufactured using current food components and technology. Food nanoemulsions, which are tiny oil droplets distributed in water, are being used as delivery methods for a variety of hydrophobic compounds, including nutrients, nutraceuticals, antioxidants, and antimicrobial agents. The present review is focused on the formulation, characterization, and applications of nanoemulsions.
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来源期刊
Current Nanomedicine
Current Nanomedicine Medicine-Medicine (miscellaneous)
CiteScore
2.00
自引率
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发文量
15
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