树状化合物在制药和工业领域的应用综述

Nagham Mahmood Aljamali
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引用次数: 0

摘要

本文综述了树枝状聚合物在药物应用中的应用。树枝状聚合物是化学和药理学领域中最重要的医用纳米聚合物,在许多药物应用中都有应用。许多生物元件如蛋白质、病毒或细菌的许多技术应用,包括色谱、光学信息技术、传感器、刺激和药物递送的应用,都需要固定或固定这些生物制品。这里,碳纳米管、金颗粒和合成聚合物可以用于这样的目的。在这里,我们注意到,这种固定化过程主要可以通过吸附或化学键合来实现,或者在较小程度上通过将这些元素作为客体结合到宿主基质中来实现。我们还注意到,在客体和宿主系统的情况下,必须建立一种固定生物元素并将其结合到基于纳米尺度的串联结构中的最佳方法,以促进生物纳米元素在其自身环境中的相互作用。这是由于大量的合成或天然聚合物可用,以及用于处理纳米纤维、棒或管等系统的先进和开发的方法,这使得聚合物成为固定不同生物材料的良好基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Review on Applications of Dendrimer-Chemical Compounds in Pharmaceutical and Industrial Fields
This review involved Dendrimer in pharmaceutical applications. Dendrimers are the most important medical nano-polymers in the fields of chemistry and pharmacology, which have been used in many pharmaceutical applications. Many technical applications of many biological elements such as proteins, viruses, or bacteria, including applications of chromatography, optical information technology, sensors, stimulation and drug delivery, require immobilization or immobilization of these biologicals. Here, carbon nanotubes, gold particles and synthetic polymers can be used for such purposes. Here we note that this immobilization process can be achieved mostly through adsorption or chemical bonding or to a lesser extent by incorporating these elements as guests in the host matrices. We also note that in the case of guest and host systems, an optimal method for immobilizing the bio-elements as well as incorporating them into a serial structure based on the nanoscale must be established to facilitate the interactions of the bio-nano-elements within their own environment. This is due to the large number of synthetic or natural polymers available and the advanced and developed methods for processing such systems for nanofibers, rods or tubes etc., this makes the polymers a good base for immobilizing different biomaterials.
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