Cone-Beam CT在癌症立体定向体放射治疗中的剂量验证

Y. Feng, Xi Liu, X. Pan, Chang Hu, Ning Zhan, Zongda Zhu, Zhenxiang Deng
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引用次数: 0

摘要

目的:利用锥束CT图像验证肺癌立体定向全身放疗(SBRT)的放射剂量分布。方法:选取20例接受SBRT治疗的肺癌患者,采用100张CBCT图像。分别用变形和非变形方法重新计算CBCT图像上的剂量分布。使用剂量-体积直方图比较计划剂量和递送剂量分布。结果:Pct与Pcbct、Pct与Pdcbct在靶体积内的平均递送靶覆盖率(V100)分别为0.83%±0.86%、1.38%±1.40%。各方案的一致性指数(CI)和梯度指数(GI)具有较好的一致性。对于关键器官,仅观察到计划剂量和递送剂量之间的微小差异。结论:CBCT图像是肺癌患者接受SBRT的有效工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Delivered Dose Verification for Lung Cancer Stereotactic Body Radiotherapy Using Cone-Beam CT
Purpose: Verified the delivered dose distribution of lung cancer Stereotactic Body Radiotherapy (SBRT) using the cone-beam CT images. Methods: Twenty lung cancer patients who underwent SBRT with 100 CBCT images were enrolled in this study. Delivered dose distributions were recalculated on CBCT images with the deformed and non-deformed methods, respectively. The planned and delivered dose distributions were compared using the dose-volume histograms. Results: The delivered target coverage (V100) per patient inside target volume deviated on average were 0.83% ± 0.86% and 1.38% ± 1.40% for Pct vs. Pcbct and Pct vs. Pdcbct, respectively. The Conformity Index (CI) and Gradient Index (GI) showed a good agreement among the plans. For the critical organs, only minor differences were observed between the planned dose and the delivered dose. Conclusions: CBCT images were a useful tool for setup and dose delivery verification for lung cancer patients who underwent SBRT.
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