脐血总IgE水平对变应性疾病的预测价值

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
G. Dib, L. Doya, M. Ismaeel, Y. Ismaeel
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引用次数: 0

摘要

儿童的过敏性疾病显著增加。近年来,它影响了高达35%的儿童。本研究旨在调查8年随访期间脐带血总IgE水平在预测过敏性疾病发展中的价值。方法——横断面研究包括2007-2015年期间在蒂什伦和阿萨德大学医院产科出生的500名婴儿。出生后进行问卷调查,包括性别、胎龄、出生体重、分娩方式和季节、怀孕期间吸烟和过敏性疾病家族史。测量脐带血总IgE水平。对这些婴儿进行了8年的随访,以了解其随后出现的过敏性疾病。结果500例新生儿中有214例(42.8%)脐血总IgE水平较高。我们对214名新生儿中的143名进行了8年的随访;51.7%的新生儿有过敏家族史。在接下来的一段时间里,76.22%的脐带血总IgE水平高的儿童出现过敏性疾病。儿童的过敏症状在鼻腔过敏(19.6%)、皮肤过敏(湿疹和荨麻疹)(25.2%)和儿童哮喘(31.5%)之间存在差异。在存在两个因素(家族史和高脐血总IgE)的情况下,过敏症状的发生率为51.7%。目前的研究可以作为一种预防策略,通过预测后续事件来降低过敏性疾病的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Predictive Value Of Umbilical Cord Blood Total IgE Levels In Allergic Diseases
Allergic diseases in children have increased significantly. In recent years, it affects up to 35% of children. The current study aimed to investigate the value of the umbilical cord blood total IgE levels in the prediction of the development of allergic diseases during 8 years of follow-up. Methods — In cross-sectional study included 500 infants who were born in the obstetrics department at Tishreen and Al-Assad University Hospitals during the period 2007-2015. Questionnaires were administered after the birth included gender, gestational age, birth weight, mode and season of delivery, smoking during pregnancy, and family history of allergic diseases. Umbilical cord blood total IgE levels were measured. The infants were followed up for eight years for subsequent development of allergic disorders. Results — 214 (42.8%) of 500 newborns had high umbilical cord blood total IgE levels. We followed 143 of 214 newborns for 8 years; there was an allergic family history in 51.7% of newborns. During the following period, allergic diseases developed in 76.22% of the children with high umbilical cord blood total IgE levels. Allergic symptoms in children varied between nasal allergy (19.6%), skin allergy (eczema and urticarial) (25.2%), childhood asthma (31.5%). The rate of allergic symptoms development in the presence of two factors (family history and high umbilical cord blood total IgE) was 51.7%. Conclusion — We found a high prevalence of allergic diseases in children with high umbilical cord blood total IgE. The current study could be used as a preventative strategy to reduce the risk of allergic diseases by predictive of subsequent.
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来源期刊
Russian Open Medical Journal
Russian Open Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
39
期刊介绍: Russian Open Medical Journal (RusOMJ) (ISSN 2304-3415) is an international peer reviewed open access e-journal. The website is updated quarterly with the RusOMJ’s latest original research, clinical studies, case reports, reviews, news, and comment articles. This Journal devoted to all field of medicine. All the RusOMJ’s articles are published in full on www.romj.org with open access and no limits on word counts. Our mission is to lead the debate on health and to engage, inform, and stimulate doctors, researchers, and other health professionals in ways that will improve outcomes for patients. The RusOMJ team is based mainly in Saratov (Russia), although we also have editors elsewhere in Russian and in other countries.
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