海藻酸钠与合成聚酸互聚配合物的水凝胶研究

IF 1 4区化学 Q4 POLYMER SCIENCE

Polymer Science, Series A Pub Date : 2023-07-03 DOI:10.1134/S0965545X23700803

I. F. Volkova, E. S. Grigoryan, G. A. Shandryuk, M. Yu. Gorshkova

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引用次数: 0

摘要

研究了合成聚酸的结构对其与海藻酸钠间聚合物配合物形成和性能的影响。水凝胶主要通过氢键形成，其类型取决于聚酸的结构和结合水的量。对水凝胶在水和рН 7.2的磷酸盐缓冲盐水中的行为进行了研究，结果表明，除了聚酸的性质外，水凝胶的性能还受组分比例和处理温度的影响。以制备利多卡因为例，探讨了水凝胶作为药物递送系统基础的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Hydrogels Based on Interpolymer Complexes of Sodium Alginate and Synthetic Polyacids

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Hydrogels Based on Interpolymer Complexes of Sodium Alginate and Synthetic Polyacids

Effect of the structure of synthetic polyacids on the formation and properties of their interpolymer complexes with sodium alginate is investigated. The hydrogels was shown to be predominantly formed via hydrogen bonds, with their type depending on the structure of polyacid and the amount of bound water. Study of the behavior of the hydrogels in water and phosphate-buffed saline with рН 7.2 demonstrates that the properties of the hydrogels are influenced by the ratio of components and the treatment temperature, in addition to the nature of polyacid. The possibility of using hydrogels as a basis for drug delivery systems is examined by the example of preparation lidocaine.

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来源期刊

Polymer Science, Series A 化学-高分子科学

CiteScore

1.70

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： Polymer Science, Series A is a journal published in collaboration with the Russian Academy of Sciences. Series A includes experimental and theoretical papers and reviews devoted to physicochemical studies of the structure and properties of polymers (6 issues a year). All journal series present original papers and reviews covering all fundamental aspects of macromolecular science. Contributions should be of marked novelty and interest for a broad readership. Articles may be written in English or Russian regardless of country and nationality of authors. All manuscripts are peer reviewed. Online submission via Internet to the Series A, B, and C is available at http://polymsci.ru.