高精度生物工程的植物启动子和终止子。

Q2 Agricultural and Biological Sciences
生物设计研究(英文) Pub Date : 2023-07-07 eCollection Date: 2023-01-01 DOI:10.34133/bdr.0013
Emily G Brooks, Estefania Elorriaga, Yang Liu, James R Duduit, Guoliang Yuan, Chung-Jui Tsai, Gerald A Tuskan, Thomas G Ranney, Xiaohan Yang, Wusheng Liu
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引用次数: 0

摘要

高精度生物工程和合成生物学需要在转录和转录后水平上微调基因表达。基因转录受到启动子和终止子的严格调控。启动子决定基因表达的时间、组织和细胞以及水平。终止子介导基因的转录终止,并在转录后影响信使核糖核酸水平,例如信使核糖核酸的3’端处理、稳定性、翻译效率和细胞核到细胞质的输出。启动子和终止子的组合影响基因表达。在本文中,我们综述了植物核心启动子、近端和远端启动子以及终止子的功能和特征,以及它们对调节基因表达的影响和基准策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Plant Promoters and Terminators for High-Precision Bioengineering.

Plant Promoters and Terminators for High-Precision Bioengineering.

Plant Promoters and Terminators for High-Precision Bioengineering.

Plant Promoters and Terminators for High-Precision Bioengineering.

High-precision bioengineering and synthetic biology require fine-tuning gene expression at both transcriptional and posttranscriptional levels. Gene transcription is tightly regulated by promoters and terminators. Promoters determine the timing, tissues and cells, and levels of the expression of genes. Terminators mediate transcription termination of genes and affect mRNA levels posttranscriptionally, e.g., the 3'-end processing, stability, translation efficiency, and nuclear to cytoplasmic export of mRNAs. The promoter and terminator combination affects gene expression. In the present article, we review the function and features of plant core promoters, proximal and distal promoters, and terminators, and their effects on and benchmarking strategies for regulating gene expression.

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CiteScore
3.90
自引率
0.00%
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审稿时长
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