心血管疾病的新生物标志物。

IF 0.9 4区 医学
Stephanie J Kim, Fernanda C P Mesquita, Camila Hochman-Mendez
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引用次数: 0

摘要

心血管疾病是全世界死亡和致残的主要原因。心血管疾病的早期发现和治疗对患者的生存和长期健康至关重要。尽管心血管疾病生物标志物取得了进展,但随着全球人口老龄化,心血管疾病的患病率在全球范围内继续增加。为了解决这个问题,必须开发对心血管疾病更敏感和更特异的新型生物标志物,并将其纳入临床实践。外泌体是心血管疾病的有前景的生物标志物。这些小泡由所有细胞产生并释放到体液中,并携带与疾病进展相关的特定信息。本文综述了现有心血管疾病生物标志物的优势和局限性,如心肌肌钙蛋白和细胞因子,并讨论了最近的证据,表明外泌体有望成为心血管疾病的生物标志物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
New Biomarkers for Cardiovascular Disease.

Cardiovascular disease is the leading cause of death and disability worldwide. Early detection and treatment of cardiovascular disease are crucial for patient survival and long-term health. Despite advances in cardiovascular disease biomarkers, the prevalence of cardiovascular disease continues to increase worldwide as the global population ages. To address this problem, novel biomarkers that are more sensitive and specific to cardiovascular diseases must be developed and incorporated into clinical practice. Exosomes are promising biomarkers for cardiovascular disease. These small vesicles are produced and released into body fluids by all cells and carry specific information that can be correlated with disease progression. This article reviews the advantages and limitations of existing biomarkers for cardiovascular disease, such as cardiac troponin and cytokines, and discusses recent evidence suggesting the promise of exosomes as cardiovascular disease biomarkers.

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来源期刊
Texas Heart Institute Journal
Texas Heart Institute Journal CARDIAC & CARDIOVASCULAR SYSTEMS-
自引率
11.10%
发文量
131
期刊介绍: For more than 45 years, the Texas Heart Institute Journal has been published by the Texas Heart Institute as part of its medical education program. Our bimonthly peer-reviewed journal enjoys a global audience of physicians, scientists, and healthcare professionals who are contributing to the prevention, diagnosis, and treatment of cardiovascular disease. The Journal was printed under the name of Cardiovascular Diseases from 1974 through 1981 (ISSN 0093-3546). The name was changed to Texas Heart Institute Journal in 1982 and was printed through 2013 (ISSN 0730-2347). In 2014, the Journal moved to online-only publication. It is indexed by Index Medicus/MEDLINE and by other indexing and abstracting services worldwide. Our full archive is available at PubMed Central. The Journal invites authors to submit these article types for review: -Clinical Investigations- Laboratory Investigations- Reviews- Techniques- Coronary Anomalies- History of Medicine- Case Reports/Case Series (Submission Fee: $70.00 USD)- Images in Cardiovascular Medicine (Submission Fee: $35.00 USD)- Guest Editorials- Peabody’s Corner- Letters to the Editor
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