直立性不耐受的选定生物标志物。

Q4 Medicine

Vnitrni lekarstvi Pub Date : 2023-01-01 DOI:10.36290/vnl.2023.066

Barbora Bačkorová, Ivica Lazúrová

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引用次数: 0

摘要

直立不耐受（OI）被定义为一组症状通常表现为站立姿势的疾病。这些症状是由大脑灌注不足引起的，在仰卧位时症状消失。这组疾病包括体位性直立性不耐受综合征（POTS）、直立性低血压（OH）和血管迷走性直立性晕厥。他们每个人都有相似的临床表现（视力模糊、虚弱、头晕、恶心、头痛、疲劳）。然而，它们在生物化学、自主神经和血液动力学特征方面各不相同。这项工作的目的是提供一个体液和非人类标志物的概述，这些标志物参与直立性不耐受的发病机制。

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Selected biomarkers of orthostatic intolerance.

Orthostatic intolerance (OI) is defined as a group of diseases which symptoms are typically manifested in a standing position. These symptoms result from cerebral hypoperfusion and disappear in the supine position. We include postural orthostatic intolerance syndrome (POTS), orthostatic hypotension (OH) and vasovagal orthostatic syncope in this group of diseases. Each of them have similar clinical presentation (blurred vision, weakness, dizziness, nausea, headaches, fatigue). However, they vary from each other in biochemical, autonomic and hemodynamic characteristics. The aim of the work is to provide an overview of humoral and non-human markers that are involved in the etiopathogenesis of orthostatic intolerance.

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来源期刊

Vnitrni lekarstvi Medicine-Internal Medicine

CiteScore

0.50

自引率

0.00%

发文量

104

期刊介绍： Vnitřní lékařství je tiskovým orgánem České internistické společnosti České lékařské společnosti Jana Evangelisty Purkyně a Slovenskej internistickej spoločnosti Slovenskej lekárskej spoločnosti. Je vydáván nepřetržitě od roku 1955. Časopis vychází jako měsíčník, tedy 12krát do roka a podle potřeby jsou v běžném ročníku vydávána jeho suplementa, která jsou obsahově zaměřena k určitému tématu. Tematicky je časopis zaměřen široce na oblast interní medicíny se zvláštní pozorností ke kardiologii, diabetologii a poruchám metabolizmu.