严重急性呼吸系统综合征冠状病毒2型感染的综合风险评估。

IF 4.6 2区 医学 Q1 NEUROSCIENCES
Molecular Neurobiology Pub Date : 2024-12-01 Epub Date: 2023-10-11 DOI:10.1007/s12035-023-03682-4
K B Megha, S Reshma, S Amir, M J Ajai Krishnan, A Shimona, Rao Alka, P V Mohanan
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引用次数: 0

摘要

大流行性新冠肺炎(2019冠状病毒病)是由严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的,该病毒摧毁了全球经济和医疗系统。感染导致新冠肺炎患者意外增加,并增加了全球死亡率。本研究对宿主与宿主的相互作用、对新冠肺炎的免疫反应、感染的恢复状态、靶向器官和相关并发症以及恢复期受试者和非感染者感染后免疫的比较提供了总体思路。变异株的出现和新冠肺炎感染事件使情况恶化。及时引入疫苗和预防措施有助于控制感染的严重程度。后来,从新冠肺炎中康复的人口大幅增长。然而,了解感染后产生的医疗保健问题的影响对于改善个人的健康状况至关重要。现在人们认识到,新冠肺炎感染影响多个器官,并表现出广泛的临床表现。因此,新冠肺炎后感染在已经流行的健康并发症患者中造成了高风险。新冠肺炎后相关健康问题的识别及其适当管理对于提高患者的生活质量更为重要。新冠肺炎涉及最初感染恢复后通常持续数周至数月的持续性、后遗症和其他并发症。在长期护理方面,多学科方法对于制定预防措施、康复技术和临床管理策略是必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comprehensive Risk Assessment of Infection Induced by SARS-CoV-2.

The pandemic COVID-19 (coronavirus disease 2019) is caused by the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2), which devastated the global economy and healthcare system. The infection caused an unforeseen rise in COVID-19 patients and increased the mortality rate globally. This study gives an overall idea about host-pathogen interaction, immune responses to COVID-19, recovery status of infection, targeted organs and complications associated, and comparison of post-infection immunity in convalescent subjects and non-infected individuals. The emergence of the variants and episodes of COVID-19 infections made the situation worsen. The timely introduction of vaccines and precautionary measures helped control the infection's severity. Later, the population that recovered from COVID-19 grew significantly. However, understanding the impact of healthcare issues resulting after infection is paramount for improving an individual's health status. It is now recognised that COVID-19 infection affects multiple organs and exhibits a broad range of clinical manifestations. So, post COVID-19 infection creates a high risk in individuals with already prevailing health complications. The identification of post-COVID-19-related health issues and their appropriate management is of greater importance to improving patient's quality of life. The persistence, sequelae and other medical complications that normally last from weeks to months after the recovery of the initial infection are involved with COVID-19. A multi-disciplinary approach is necessary for the development of preventive measures, techniques for rehabilitation and strategies for clinical management when it comes to long-term care.

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来源期刊
Molecular Neurobiology
Molecular Neurobiology 医学-神经科学
CiteScore
9.00
自引率
2.00%
发文量
480
审稿时长
1 months
期刊介绍: Molecular Neurobiology is an exciting journal for neuroscientists needing to stay in close touch with progress at the forefront of molecular brain research today. It is an especially important periodical for graduate students and "postdocs," specifically designed to synthesize and critically assess research trends for all neuroscientists hoping to stay active at the cutting edge of this dramatically developing area. This journal has proven to be crucial in departmental libraries, serving as essential reading for every committed neuroscientist who is striving to keep abreast of all rapid developments in a forefront field. Most recent significant advances in experimental and clinical neuroscience have been occurring at the molecular level. Until now, there has been no journal devoted to looking closely at this fragmented literature in a critical, coherent fashion. Each submission is thoroughly analyzed by scientists and clinicians internationally renowned for their special competence in the areas treated.
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