{"title":"【大脑“内部GPS”的研究与发现】。","authors":"T T Chen, Z P Li","doi":"10.3760/cma.j.cn112155-20221214-00177","DOIUrl":null,"url":null,"abstract":"<p><p>Since the 20th century, with the progress of brain science research, scientists have discovered the brain GPS, revealing the mechanism of brain spatial cognition. The discovery process of brain GPS has gone through three stages. In 1971, John O'Keefe discovered the position cells in the hippocampus of the brain, which was the beginning of the research on the GPS in the brain; In 1900, James Rank discovered the head direction cells in the medial entorhinal cortex of the brain, and the research on the GPS in the brain made a breakthrough; In 2005, Edvard I. Moser and his wife discovered grid cells, marking the maturity of the research on GPS in the brain. The discovery of intracerebral GPS not only reveals the spatial cognitive function of the brain at the cellular level, but also provides a theoretical basis for the study of diseases related to the nervous system.</p>","PeriodicalId":35995,"journal":{"name":"中华医史杂志","volume":"53 4","pages":"251-256"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Research and discovery of \\\"inner GPS\\\" of brain].\",\"authors\":\"T T Chen, Z P Li\",\"doi\":\"10.3760/cma.j.cn112155-20221214-00177\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Since the 20th century, with the progress of brain science research, scientists have discovered the brain GPS, revealing the mechanism of brain spatial cognition. The discovery process of brain GPS has gone through three stages. In 1971, John O'Keefe discovered the position cells in the hippocampus of the brain, which was the beginning of the research on the GPS in the brain; In 1900, James Rank discovered the head direction cells in the medial entorhinal cortex of the brain, and the research on the GPS in the brain made a breakthrough; In 2005, Edvard I. Moser and his wife discovered grid cells, marking the maturity of the research on GPS in the brain. The discovery of intracerebral GPS not only reveals the spatial cognitive function of the brain at the cellular level, but also provides a theoretical basis for the study of diseases related to the nervous system.</p>\",\"PeriodicalId\":35995,\"journal\":{\"name\":\"中华医史杂志\",\"volume\":\"53 4\",\"pages\":\"251-256\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中华医史杂志\",\"FirstCategoryId\":\"1090\",\"ListUrlMain\":\"https://doi.org/10.3760/cma.j.cn112155-20221214-00177\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中华医史杂志","FirstCategoryId":"1090","ListUrlMain":"https://doi.org/10.3760/cma.j.cn112155-20221214-00177","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Since the 20th century, with the progress of brain science research, scientists have discovered the brain GPS, revealing the mechanism of brain spatial cognition. The discovery process of brain GPS has gone through three stages. In 1971, John O'Keefe discovered the position cells in the hippocampus of the brain, which was the beginning of the research on the GPS in the brain; In 1900, James Rank discovered the head direction cells in the medial entorhinal cortex of the brain, and the research on the GPS in the brain made a breakthrough; In 2005, Edvard I. Moser and his wife discovered grid cells, marking the maturity of the research on GPS in the brain. The discovery of intracerebral GPS not only reveals the spatial cognitive function of the brain at the cellular level, but also provides a theoretical basis for the study of diseases related to the nervous system.
期刊介绍:
The Chinese Journal of Medical History is the only professional academic journal on medical history in the country. The first publication was named "Journal of Medical History" and was designated as a quarterly publication. In 2009, it was changed from quarterly to bimonthly.
The Chinese Journal of Medical History has columns such as special articles, reviews, expert talks, medical history treatises, literature research, forums and debates, historical accounts, figures, short essays, graduate forums, lectures, historical materials, medical history, and book reviews.
Chinese Journal of Medical History has been included in the US Medline online database.