抗微生物耐药性及其检测方法。

Olga I Guliy, Stella S Evstigneeva, Olga A Karavaeva
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引用次数: 0

摘要

感染诊断和抗生素敏感性测试是临床微生物学的重要方面,由于目前在早期检测细菌对抗生素反应方面的标准不足,这些方面急需改进。抗微生物耐药性的增加是对人类健康的严重全球威胁。目前的耐药性检测方法,使用表型抗生素敏感性测试,测量受抗生素影响的细菌生长,分析时间很长。因此,需要新的、快速的方法来检测抗生素耐药性。在这里,我们回顾了用于检测细菌抗生素耐药性的方法,包括由生物膜发育引起的耐药性,并展望了评估抗生素耐药性(AMR)的快速方法的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antimicrobial Resistance and Current Methods for its Detection.

Infection diagnosis and antibiotic sensitivity testing are important aspects of clinical microbiology that are in dire need of improvement owing to the inadequate current standards in the early detection of bacterial response to antibiotics. The increasing antimicrobial resistance is a serious global threat to human health. Current resistance-detecting methods, using the phenotypic antibiotic sensitivity test, which measures bacterial growth as affected by antibiotics, have long analysis times. Therefore, new and rapid methods are needed to detect antibiotic resistance. Here, we review the methods used to detect antibiotic resistance in bacteria, including that caused by biofilm development, and we look at the development of rapid methods for evaluating antimicrobial resistance (AMR).

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