David Eric O'Neill, Bhavani Gannavarapu, Brian Hrycushko, Michael Folkert, Robert Timmerman, Alexandra Callan
{"title":"髓内近距离放射治疗长骨转移性疾病：一例报告。","authors":"David Eric O'Neill, Bhavani Gannavarapu, Brian Hrycushko, Michael Folkert, Robert Timmerman, Alexandra Callan","doi":"10.1097/OI9.0000000000000267","DOIUrl":null,"url":null,"abstract":"<p><strong>Case: </strong>A 56-year-old woman with metastatic melanoma and femoral lesions with impending pathologic fracture was indicated for intramedullary brachytherapy (IMBT) and intramedullary nail.</p><p><strong>Conclusions: </strong>IMBT + intramedullary nail is a new technique for the treatment of long bone metastases. IMBT maximizes radiation to the tumor and minimizes radiation to surrounding tissues. It allows the patient to resume systemic treatment expediently. Our cadaver model and patient were both treated for femoral metastases; however, this technique allows for the treatment of any long bone. This is a safe technique that minimizes treatment time compared with other standard radiation regimens.</p>","PeriodicalId":74381,"journal":{"name":"OTA international : the open access journal of orthopaedic trauma","volume":"6 2","pages":"e267"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ac/74/oi9-6-e267.PMC10538573.pdf","citationCount":"0","resultStr":"{\"title\":\"Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report.\",\"authors\":\"David Eric O'Neill, Bhavani Gannavarapu, Brian Hrycushko, Michael Folkert, Robert Timmerman, Alexandra Callan\",\"doi\":\"10.1097/OI9.0000000000000267\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Case: </strong>A 56-year-old woman with metastatic melanoma and femoral lesions with impending pathologic fracture was indicated for intramedullary brachytherapy (IMBT) and intramedullary nail.</p><p><strong>Conclusions: </strong>IMBT + intramedullary nail is a new technique for the treatment of long bone metastases. IMBT maximizes radiation to the tumor and minimizes radiation to surrounding tissues. It allows the patient to resume systemic treatment expediently. Our cadaver model and patient were both treated for femoral metastases; however, this technique allows for the treatment of any long bone. This is a safe technique that minimizes treatment time compared with other standard radiation regimens.</p>\",\"PeriodicalId\":74381,\"journal\":{\"name\":\"OTA international : the open access journal of orthopaedic trauma\",\"volume\":\"6 2\",\"pages\":\"e267\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ac/74/oi9-6-e267.PMC10538573.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"OTA international : the open access journal of orthopaedic trauma\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/OI9.0000000000000267\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/6/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"OTA international : the open access journal of orthopaedic trauma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/OI9.0000000000000267","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/6/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Intramedullary brachytherapy for the treatment of long bone metastatic disease: A case report.
Case: A 56-year-old woman with metastatic melanoma and femoral lesions with impending pathologic fracture was indicated for intramedullary brachytherapy (IMBT) and intramedullary nail.
Conclusions: IMBT + intramedullary nail is a new technique for the treatment of long bone metastases. IMBT maximizes radiation to the tumor and minimizes radiation to surrounding tissues. It allows the patient to resume systemic treatment expediently. Our cadaver model and patient were both treated for femoral metastases; however, this technique allows for the treatment of any long bone. This is a safe technique that minimizes treatment time compared with other standard radiation regimens.
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