病毒性戊型肝炎，人畜共患传播在阿尔及利亚。

Q2 Medicine

VirusDisease Pub Date : 2023-09-01 Epub Date: 2023-09-19 DOI:10.1007/s13337-023-00840-z

Houda Boukhrissa, Salah Mechakra, Abbes Mahnane, Abdelmadjid Lacheheb

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引用次数: 0

摘要

戊型病毒性肝炎是成人急性病毒性肝炎的主要原因，也是一个全球性的公共卫生问题。该病毒的人畜共患潜力目前已被发达国家所接受。在主要通过肠道传播的发展中国家，有关动物宿主的数据非常有限。我们的目标是确定我们地区（阿尔及利亚东部）可能存在的人畜共患传播风险。使用商业ELISA试剂盒通过ti HEV IgG抗体检测来分析来自献血者的四百三十四份血清。研究参与者被问及人口统计数据、与农场动物、宠物、老鼠的接触以及狩猎活动中的现场或射击游戏。抗HEV IgG血清阳性率为17.05%；大鼠接触的血清流行率为51.2%（p p = 0.003），或 = 2.76[95%CI 1.37-5.56]。总之，我们地区可能存在人畜共患传播。应调查老鼠和猎物是否有可能的动物宿主。

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Viral hepatitis E, zoonotic transmission in Algeria.

Viral hepatitis E, a major cause of acute viral hepatitis in adults, is a global public health problem. The zoonotic potential of the virus is currently accepted in developed countries. In developing countries, where transmission is mainly enteric, data on the animal reservoir are very limited. Our objective was to identify a possible risk of zoonotic transmission in our region (eastern Algeria). Four hundred and thirty four sera from blood donors were analysed by an-ti-HEV IgG antibodies detection using a commercial ELISA kit. Study participants were asked about demographics, contact with farm animals, pets, rats, and with live or shot game during a hunting activity. The anti-HEV IgG seroprevalence was 17.05%. Two risk factors were identified; rat contact with a seroprevalence rate at 51.2% (p < 1p.1000), OR = 6.736 [95% CI 3, 42-13.26] and game contact with a seroprevalence at 33% (p = 0.003), OR = 2.76 [95% CI 1.37-5.56]. In summary, zoonotic transmission is possible in our region. Rats and game should be investigated for a probable animal reservoir.

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来源期刊

VirusDisease Medicine-Infectious Diseases

CiteScore

7.00

自引率

0.00%

发文量

期刊介绍： VirusDisease, formerly known as ''Indian Journal of Virology'', publishes original research on all aspects of viruses infecting animal, human, plant, fish and other living organisms.