上颌后部鳞状牙源性肿瘤。

IF 3.2 Q2 PATHOLOGY
Head & Neck Pathology Pub Date : 2023-12-01 Epub Date: 2023-09-28 DOI:10.1007/s12105-023-01585-3
John Lennon Silva Cunha, Bruno Augusto Benevenuto de Andrade, Israel Leal Cavalcante, Clara Herrera Freire, Nathália de Almeida Freire, Sarah Aparecida Ferreira Antero, Fábio Ramôa Pires, Mônica Simões Israel
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引用次数: 0

摘要

鳞状牙源性肿瘤(SOT)是一种罕见的良性但局部浸润性肿瘤,由于形态学发现重叠,常被误诊为其他实体,如成釉细胞瘤和鳞状细胞癌。我们在此记录了一名25岁男性患者上颌骨左后区骨内侵袭性SOT的临床病理和影像学表现。在口腔内检查中,肿瘤从左侧切牙区域延伸到左上前臼齿,并被红色粘膜覆盖,有离散的溃疡区域。影像学检查显示,与受影响犬相关的溶骨性病变导致变薄、侵蚀和颊舌皮质板穿孔。显微镜下,肿瘤显示分化良好的鳞状上皮岛在不同的胶原背景下增殖。岛的外周细胞是扁平的或略呈立方体,并且没有表现出具有外周栅栏和反向极化的细胞核。诊断为SOT。患者接受了手术切除,并接受了大约12个月的临床随访,没有复发迹象。仔细的形态学评估对于避免误诊和确保满意的治疗方法至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Squamous Odontogenic Tumor in the Posterior Region of Maxilla.

Squamous odontogenic tumor (SOT) is a rare benign but locally infiltrative tumor often misdiagnosed as other entities, such as ameloblastoma and squamous cell carcinoma, due to overlapping morphological findings. We document here the clinicopathological and imaging findings of an aggressive intraosseous SOT in the posterior left region of the maxilla in a 25-year-old male patient. On intraoral examination, the tumor extended from the region of the left lateral incisor to the upper left premolar and was covered by reddish mucosa, with discrete areas of ulceration. Imaging exams revealed an osteolytic lesion causing thinning, erosion, and buccal and lingual cortical plate perforation associated with an impacted canine. Microscopically, the tumor showed a proliferation of islands of well-differentiated squamous epithelium in a variably collagenized background. The peripheral cells of the islands were flat or slightly cuboidal and did not exhibit nuclei with peripheral palisade and reverse polarization. The diagnosis of SOT was rendered. The patient underwent surgical resection and has been under clinical follow-up for approximately 12 months with no signs of recurrence. A careful morphological evaluation is essential to avoid misdiagnosis and ensure a satisfactory treatment approach.

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来源期刊
CiteScore
5.70
自引率
9.50%
发文量
99
期刊介绍: Head & Neck Pathology presents scholarly papers, reviews and symposia that cover the spectrum of human surgical pathology within the anatomic zones of the oral cavity, sinonasal tract, larynx, hypopharynx, salivary gland, ear and temporal bone, and neck. The journal publishes rapid developments in new diagnostic criteria, intraoperative consultation, immunohistochemical studies, molecular techniques, genetic analyses, diagnostic aids, experimental pathology, cytology, radiographic imaging, and application of uniform terminology to allow practitioners to continue to maintain and expand their knowledge in the subspecialty of head and neck pathology. Coverage of practical application to daily clinical practice is supported with proceedings and symposia from international societies and academies devoted to this field. Single-blind peer review The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.
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