Young Hoon Chang, Cheol Min Shin, Dong Ho Lee, Hyuk Yoon, Young Soo Park, Nayoung Kim
{"title":"幽门螺杆菌感染与嗜酸性食管炎的关系。","authors":"Young Hoon Chang, Cheol Min Shin, Dong Ho Lee, Hyuk Yoon, Young Soo Park, Nayoung Kim","doi":"10.4166/kjg.2023.037","DOIUrl":null,"url":null,"abstract":"<p><strong>Background/aims: </strong>This study examined the association between eosinophilic esophagitis (EoE) and <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection.</p><p><strong>Methods: </strong>A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy.</p><p><strong>Results: </strong>Although 17 out of 90 (18.9%) controls had a <i>H. pylori</i> infection, only two out of 45 (4.4%) EoE patients showed evidence of a <i>H. pylori</i> infection. EoE was inversely associated with a <i>H. pylori</i> infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044).</p><p><strong>Conclusions: </strong>An inverse association was observed between <i>H. pylori</i> infection and EoE. Further prospective studies will be needed to validate the protective effects of <i>H. pylori</i> infection for EoE.</p>","PeriodicalId":94245,"journal":{"name":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association between <i>Helicobacter pylori</i> Infection and Eosinophilic Esophagitis.\",\"authors\":\"Young Hoon Chang, Cheol Min Shin, Dong Ho Lee, Hyuk Yoon, Young Soo Park, Nayoung Kim\",\"doi\":\"10.4166/kjg.2023.037\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background/aims: </strong>This study examined the association between eosinophilic esophagitis (EoE) and <i>Helicobacter pylori</i> (<i>H. pylori</i>) infection.</p><p><strong>Methods: </strong>A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy.</p><p><strong>Results: </strong>Although 17 out of 90 (18.9%) controls had a <i>H. pylori</i> infection, only two out of 45 (4.4%) EoE patients showed evidence of a <i>H. pylori</i> infection. EoE was inversely associated with a <i>H. pylori</i> infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044).</p><p><strong>Conclusions: </strong>An inverse association was observed between <i>H. pylori</i> infection and EoE. Further prospective studies will be needed to validate the protective effects of <i>H. pylori</i> infection for EoE.</p>\",\"PeriodicalId\":94245,\"journal\":{\"name\":\"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4166/kjg.2023.037\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4166/kjg.2023.037","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Association between Helicobacter pylori Infection and Eosinophilic Esophagitis.
Background/aims: This study examined the association between eosinophilic esophagitis (EoE) and Helicobacter pylori (H. pylori) infection.
Methods: A single tertiary referral center case-control study was performed. EoE patients diagnosed at Seoul National University Bundang Hospital from July 2003 to March 2022 were reviewed retrospectively. Forty-five EoE patients were included in the analysis. For each EoE patient, two age and sex-matched normal controls were selected randomly from an outpatient population who received upper gastrointestinal endoscopy.
Results: Although 17 out of 90 (18.9%) controls had a H. pylori infection, only two out of 45 (4.4%) EoE patients showed evidence of a H. pylori infection. EoE was inversely associated with a H. pylori infection (odds ratio 0.20, 95% confidence interval 0.04-0.91, p=0.044).
Conclusions: An inverse association was observed between H. pylori infection and EoE. Further prospective studies will be needed to validate the protective effects of H. pylori infection for EoE.
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