确保苄星苄青霉素的供应：全球风险视角和预防未来短缺的缓解策略。

IF 2.3 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Health Pub Date : 2024-05-01 DOI:10.1093/inthealth/ihad087

Frederic Seghers, Melanie M Taylor, Andrew Storey, Jicui Dong, Teodora C Wi, Rosemary Wyber, Kate Ralston, Boniface Dongmo Nguimfack

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引用次数: 0

摘要

苄脒苄青霉素是全球不可或缺的药物。作为一种长效注射青霉素，它是治疗梅毒、a组链球菌感染、风湿热和风湿性心脏病的主要药物。竞争激烈的市场和低利润率，再加上需求的有限可见性，导致API制造商的数量减少。到2016年，中国API制造商只剩下三家，继续向全球市场供应。全球供应和需求失衡的结果是不断出现的短缺，这表明了潜在的市场风险。因此，迫切需要制定缓解战略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Securing the supply of benzathine penicillin: a global perspective on risks and mitigation strategies to prevent future shortages.

Benzathine benzylpenicillin is a globally indispensable medicine. As a long-lasting injectable penicillin, it serves as the primary treatment for syphilis, group A streptococcal infections, rheumatic fever and rheumatic heart disease. A competitive market and low profit margins, compounded by limited visibility of demand, have resulted in a decreased number of active pharmaceutical ingredient (API) manufacturers. By 2016, only three Chinese API manufacturers remained, continuing to supply to the global market today. Recurring global shortages, a consequence of supply and demand imbalances, indicate underlying market risks. Therefore, the need for mitigation strategies is imperative.

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来源期刊

International Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： International Health is an official journal of the Royal Society of Tropical Medicine and Hygiene. It publishes original, peer-reviewed articles and reviews on all aspects of global health including the social and economic aspects of communicable and non-communicable diseases, health systems research, policy and implementation, and the evaluation of disease control programmes and healthcare delivery solutions. It aims to stimulate scientific and policy debate and provide a forum for analysis and opinion sharing for individuals and organisations engaged in all areas of global health.