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合成苯二氮卓类药物的流动平台

IF 2 4区 化学 Q3 CHEMISTRY, MULTIDISCIPLINARY
Journal of Flow Chemistry Pub Date : 2022-11-02 DOI:10.1007/s41981-022-00243-z
Maria Ivanova, Thomas Poisson, Philippe Jubault, Julien Legros
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引用次数: 1

摘要

苯二氮卓类药物具有广泛的药理作用，是主要药物之一，通常用于治疗各种疾病。在这里，我们描述了六种苯二氮卓类药物的连续流合成:地西泮，氟地西泮，去甲达西泮，硝西泮，氯硝西泮，恶西泮。
本文章由计算机程序翻译，如有差异，请以英文原文为准。

Flow platform for the synthesis of benzodiazepines

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Flow platform for the synthesis of benzodiazepines

Benzodiazepines possess a wide spectrum of valuable pharmacological effects and are among the leading drugs, commonly prescribed ones for various pathologies. Herein we describe the continuous flow synthesis of six benzodiazepines from aminobenzophenones: diazepam, fludiazepam, nordazepam, nitrazepam, clonazepam, oxazepam.

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来源期刊
Journal of Flow Chemistry
Journal of Flow Chemistry CHEMISTRY, MULTIDISCIPLINARY-
CiteScore
6.40
自引率
3.70%
发文量
29
审稿时长
>12 weeks
期刊介绍： The main focus of the journal is flow chemistry in inorganic, organic, analytical and process chemistry in the academic research as well as in applied research and development in the pharmaceutical, agrochemical, fine-chemical, petro- chemical, fragrance industry.
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