{"title":"研究过氧化氢生物医学应用的物理化学方法","authors":"E. V. Stepanov, I. A. Shcherbakov","doi":"10.3103/S1541308X23020103","DOIUrl":null,"url":null,"abstract":"<p>The role of hydrogen peroxide molecule (Н<sub>2</sub>О<sub>2</sub>) in the vital functions of biological objects has been considered. The mechanisms of Н<sub>2</sub>О<sub>2</sub> formation and its relationship with redox reactions, as well as some possible methods of analyzing the Н<sub>2</sub>О<sub>2</sub> content in liquid and gaseous media, are discussed. In particular, the possibility of using highly sensitive methods of laser spectral analysis for detecting Н<sub>2</sub>О<sub>2</sub> traces in exhaled air, which are promising for diagnostics of various pathologies, is considered. The absorption spectra of exhaled air are analyzed, and the strongest H<sub>2</sub>O<sub>2</sub> spectral lines (isolated from the influence of other gaseous metabolites), applicable for detecting Н<sub>2</sub>О<sub>2</sub> by diode laser spectroscopy, are chosen.</p>","PeriodicalId":732,"journal":{"name":"Physics of Wave Phenomena","volume":"31 2","pages":"92 - 97"},"PeriodicalIF":1.1000,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Physicochemical Methods of Studying Hydrogen Peroxide for Biomedical Applications\",\"authors\":\"E. V. Stepanov, I. A. Shcherbakov\",\"doi\":\"10.3103/S1541308X23020103\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>The role of hydrogen peroxide molecule (Н<sub>2</sub>О<sub>2</sub>) in the vital functions of biological objects has been considered. The mechanisms of Н<sub>2</sub>О<sub>2</sub> formation and its relationship with redox reactions, as well as some possible methods of analyzing the Н<sub>2</sub>О<sub>2</sub> content in liquid and gaseous media, are discussed. In particular, the possibility of using highly sensitive methods of laser spectral analysis for detecting Н<sub>2</sub>О<sub>2</sub> traces in exhaled air, which are promising for diagnostics of various pathologies, is considered. The absorption spectra of exhaled air are analyzed, and the strongest H<sub>2</sub>O<sub>2</sub> spectral lines (isolated from the influence of other gaseous metabolites), applicable for detecting Н<sub>2</sub>О<sub>2</sub> by diode laser spectroscopy, are chosen.</p>\",\"PeriodicalId\":732,\"journal\":{\"name\":\"Physics of Wave Phenomena\",\"volume\":\"31 2\",\"pages\":\"92 - 97\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2023-05-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physics of Wave Phenomena\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://link.springer.com/article/10.3103/S1541308X23020103\",\"RegionNum\":4,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"PHYSICS, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics of Wave Phenomena","FirstCategoryId":"101","ListUrlMain":"https://link.springer.com/article/10.3103/S1541308X23020103","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PHYSICS, MULTIDISCIPLINARY","Score":null,"Total":0}
Physicochemical Methods of Studying Hydrogen Peroxide for Biomedical Applications
The role of hydrogen peroxide molecule (Н2О2) in the vital functions of biological objects has been considered. The mechanisms of Н2О2 formation and its relationship with redox reactions, as well as some possible methods of analyzing the Н2О2 content in liquid and gaseous media, are discussed. In particular, the possibility of using highly sensitive methods of laser spectral analysis for detecting Н2О2 traces in exhaled air, which are promising for diagnostics of various pathologies, is considered. The absorption spectra of exhaled air are analyzed, and the strongest H2O2 spectral lines (isolated from the influence of other gaseous metabolites), applicable for detecting Н2О2 by diode laser spectroscopy, are chosen.
期刊介绍：
Physics of Wave Phenomena publishes original contributions in general and nonlinear wave theory, original experimental results in optics, acoustics and radiophysics. The fields of physics represented in this journal include nonlinear optics, acoustics, and radiophysics; nonlinear effects of any nature including nonlinear dynamics and chaos; phase transitions including light- and sound-induced; laser physics; optical and other spectroscopies; new instruments, methods, and measurements of wave and oscillatory processes; remote sensing of waves in natural media; wave interactions in biophysics, econophysics and other cross-disciplinary areas.
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