{"title":"干细胞存在于老鼠尾巴的证据。","authors":"C V ROBINSON, S L COMMERFORD, J L BATEMAN","doi":"10.3181/00379727-119-30142","DOIUrl":null,"url":null,"abstract":"Summary In experiments in which the tails of mice were shielded during exposure to X-rays, colonization of the spleen occurred in excess of that found in whole-body irradiated control animals. This was the case whether the measure of effect was post-irradiative gain in spleen weight, uptake of IDU (5-iodo-2′-deoxyuridine), or nodule count. The degree of colonization was found to be a function of the length of time which elapsed between the original irradiation (with tail shielded) and a subsequent, suppressive irradiation of the tail. Histological examination showed that the spleen nodules were hemopoietic, and that normal tail vertebrae contained hemopoietic tissue.","PeriodicalId":20675,"journal":{"name":"Proceedings of the Society for Experimental Biology and Medicine","volume":" ","pages":"222-6"},"PeriodicalIF":0.0000,"publicationDate":"1965-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3181/00379727-119-30142","citationCount":"23","resultStr":"{\"title\":\"EVIDENCE FOR THE PRESENCE OF STEM CELLS IN THE TAIL OF THE MOUSE.\",\"authors\":\"C V ROBINSON, S L COMMERFORD, J L BATEMAN\",\"doi\":\"10.3181/00379727-119-30142\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Summary In experiments in which the tails of mice were shielded during exposure to X-rays, colonization of the spleen occurred in excess of that found in whole-body irradiated control animals. This was the case whether the measure of effect was post-irradiative gain in spleen weight, uptake of IDU (5-iodo-2′-deoxyuridine), or nodule count. The degree of colonization was found to be a function of the length of time which elapsed between the original irradiation (with tail shielded) and a subsequent, suppressive irradiation of the tail. Histological examination showed that the spleen nodules were hemopoietic, and that normal tail vertebrae contained hemopoietic tissue.\",\"PeriodicalId\":20675,\"journal\":{\"name\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"volume\":\" \",\"pages\":\"222-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1965-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3181/00379727-119-30142\",\"citationCount\":\"23\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3181/00379727-119-30142\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Society for Experimental Biology and Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3181/00379727-119-30142","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
EVIDENCE FOR THE PRESENCE OF STEM CELLS IN THE TAIL OF THE MOUSE.
Summary In experiments in which the tails of mice were shielded during exposure to X-rays, colonization of the spleen occurred in excess of that found in whole-body irradiated control animals. This was the case whether the measure of effect was post-irradiative gain in spleen weight, uptake of IDU (5-iodo-2′-deoxyuridine), or nodule count. The degree of colonization was found to be a function of the length of time which elapsed between the original irradiation (with tail shielded) and a subsequent, suppressive irradiation of the tail. Histological examination showed that the spleen nodules were hemopoietic, and that normal tail vertebrae contained hemopoietic tissue.