R L TYNDALL, J G VIDRINE, E TEETER, A C UPTON, W W HARRIS, M A FINK
{"title":"感染小鼠白血病病毒的细胞培养物的细胞致病性效应。","authors":"R L TYNDALL, J G VIDRINE, E TEETER, A C UPTON, W W HARRIS, M A FINK","doi":"10.3181/00379727-119-30132","DOIUrl":null,"url":null,"abstract":"Summary Cell cultures grown in modified NCTC 109 medium and infected with the Rauscher leukemia virus showed CPE when subcultured in Eagle's basal medium. Non-infected control cultures treated in a similar manner showed no CPE. The CPE in infected cultures included increased cytoplasmic eosin-ophilia in the form of either eosinophilic granules or inclusion bodies, cytoplasmic vacuolization, and marked variation in the size, shape, and intensity of staining of cell nuclei.","PeriodicalId":20675,"journal":{"name":"Proceedings of the Society for Experimental Biology and Medicine","volume":" ","pages":"186-9"},"PeriodicalIF":0.0000,"publicationDate":"1965-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3181/00379727-119-30132","citationCount":"6","resultStr":"{\"title\":\"CYTOPATHOGENIC EFFECTS IN A CELL CULTURE INFECTED WITH A MURINE LEUKEMIA VIRUS.\",\"authors\":\"R L TYNDALL, J G VIDRINE, E TEETER, A C UPTON, W W HARRIS, M A FINK\",\"doi\":\"10.3181/00379727-119-30132\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Summary Cell cultures grown in modified NCTC 109 medium and infected with the Rauscher leukemia virus showed CPE when subcultured in Eagle's basal medium. Non-infected control cultures treated in a similar manner showed no CPE. The CPE in infected cultures included increased cytoplasmic eosin-ophilia in the form of either eosinophilic granules or inclusion bodies, cytoplasmic vacuolization, and marked variation in the size, shape, and intensity of staining of cell nuclei.\",\"PeriodicalId\":20675,\"journal\":{\"name\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"volume\":\" \",\"pages\":\"186-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1965-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3181/00379727-119-30132\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3181/00379727-119-30132\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Society for Experimental Biology and Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3181/00379727-119-30132","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
CYTOPATHOGENIC EFFECTS IN A CELL CULTURE INFECTED WITH A MURINE LEUKEMIA VIRUS.
Summary Cell cultures grown in modified NCTC 109 medium and infected with the Rauscher leukemia virus showed CPE when subcultured in Eagle's basal medium. Non-infected control cultures treated in a similar manner showed no CPE. The CPE in infected cultures included increased cytoplasmic eosin-ophilia in the form of either eosinophilic granules or inclusion bodies, cytoplasmic vacuolization, and marked variation in the size, shape, and intensity of staining of cell nuclei.
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