Kurt H. Stenzel , Glenn D. Lubash , Peter F. Davison , Albert L. Rubin
{"title":"三氯乙酸溶性血浆蛋白的特征及其在肾功能不全中的变化","authors":"Kurt H. Stenzel , Glenn D. Lubash , Peter F. Davison , Albert L. Rubin","doi":"10.1016/0926-6526(64)90040-0","DOIUrl":null,"url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. Protein material in 5% trichloroacetic acid extracts of human plasma appears physically homogeneous and closely resembles <em>α</em><sub>1</sub>-acid glycoprotein (orosomucoid). Molecular weight is estimated at 41000 (±2000), <em>E</em><sub>1%,icm<sup>278</sup></sub> is 7.7, and the protein has a high carbohydrate and sialic acid content.</p></span></li><li><span>2.</span><span><p>2. Concentrations of this protein are markedly elevated in renal insufficiency.</p></span></li></ul></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 2","pages":"Pages 231-236"},"PeriodicalIF":0.0000,"publicationDate":"1964-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90040-0","citationCount":"2","resultStr":"{\"title\":\"Characterization of trichloroacetic acid-soluble plasma protein and its variations in renal insufficiency\",\"authors\":\"Kurt H. Stenzel , Glenn D. Lubash , Peter F. Davison , Albert L. Rubin\",\"doi\":\"10.1016/0926-6526(64)90040-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p></p><ul><li><span>1.</span><span><p>1. Protein material in 5% trichloroacetic acid extracts of human plasma appears physically homogeneous and closely resembles <em>α</em><sub>1</sub>-acid glycoprotein (orosomucoid). Molecular weight is estimated at 41000 (±2000), <em>E</em><sub>1%,icm<sup>278</sup></sub> is 7.7, and the protein has a high carbohydrate and sialic acid content.</p></span></li><li><span>2.</span><span><p>2. Concentrations of this protein are markedly elevated in renal insufficiency.</p></span></li></ul></div>\",\"PeriodicalId\":100172,\"journal\":{\"name\":\"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides\",\"volume\":\"83 2\",\"pages\":\"Pages 231-236\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1964-07-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0926-6526(64)90040-0\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0926652664900400\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0926652664900400","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Characterization of trichloroacetic acid-soluble plasma protein and its variations in renal insufficiency
1.
1. Protein material in 5% trichloroacetic acid extracts of human plasma appears physically homogeneous and closely resembles α1-acid glycoprotein (orosomucoid). Molecular weight is estimated at 41000 (±2000), E1%,icm278 is 7.7, and the protein has a high carbohydrate and sialic acid content.
2.
2. Concentrations of this protein are markedly elevated in renal insufficiency.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
