{"title":"哪些血液和内分泌指标对 COVID-19 感染很重要？","authors":"Alireza Ostadrahimi, Vahideh Sadra, Amir Bahrami, Zohreh Razzaghi, Mostafa Najafipour, Helda Tutunchi, Farzad Najafipour","doi":"10.34172/hpp.2022.26","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background:</b> Clinical evidence of endocrine involvement in coronavirus disease needs further investigation. The aim of the present study was to assess the relationship between hematology and endocrine parameters in coronavirus disease 2019 (COVID-19) infection. <b>Methods:</b> In the present cross-sectional study, a total of 320 patients (215 survivors and 105 non-survivors) with confirmed COVID-19 infection were enrolled. After isolation of serum samples, hematological, biochemical, and hormonal parameters were analyzed. <b>Results:</b> The mean age of survivors and non-survivors was 58.92 (SD: 15.28) and 63.65 (SD: 16.62) years, respectively. The results demonstrated significant differences in free triiodothyronine (FT3) [MD (95% CI): 0.40 (0.10, 0.71), <i>P</i>=0.009], total calcium [MD (95% CI): 0.53 (0.21, 0.86), <i>P</i>=0.003], vitamin D [MD (95% CI): 7.72 (6.38, 9.05), <i>P</i>=0.003], erythrocyte sedimentation rate (ESR) [MD (95% CI): 17.09 (9.38, 22.05), <i>P</i>=0.004) and serum ferritin [Median difference: -1091.9, <i>P</i><0.001), between survivors and non-survivors, respectively. <b>Conclusion:</b> The results revealed that some hematological and endocrine factors play an important role in prognosis of COVID-19 infection. However, further studies with a larger population are required to clarify the exact effects of COVID-19 on the endocrine system.</p>","PeriodicalId":46588,"journal":{"name":"Health Promotion Perspectives","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508391/pdf/","citationCount":"0","resultStr":"{\"title\":\"What hematological and endocrinal indicators are important in COVID-19 infection?\",\"authors\":\"Alireza Ostadrahimi, Vahideh Sadra, Amir Bahrami, Zohreh Razzaghi, Mostafa Najafipour, Helda Tutunchi, Farzad Najafipour\",\"doi\":\"10.34172/hpp.2022.26\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Background:</b> Clinical evidence of endocrine involvement in coronavirus disease needs further investigation. The aim of the present study was to assess the relationship between hematology and endocrine parameters in coronavirus disease 2019 (COVID-19) infection. <b>Methods:</b> In the present cross-sectional study, a total of 320 patients (215 survivors and 105 non-survivors) with confirmed COVID-19 infection were enrolled. After isolation of serum samples, hematological, biochemical, and hormonal parameters were analyzed. <b>Results:</b> The mean age of survivors and non-survivors was 58.92 (SD: 15.28) and 63.65 (SD: 16.62) years, respectively. The results demonstrated significant differences in free triiodothyronine (FT3) [MD (95% CI): 0.40 (0.10, 0.71), <i>P</i>=0.009], total calcium [MD (95% CI): 0.53 (0.21, 0.86), <i>P</i>=0.003], vitamin D [MD (95% CI): 7.72 (6.38, 9.05), <i>P</i>=0.003], erythrocyte sedimentation rate (ESR) [MD (95% CI): 17.09 (9.38, 22.05), <i>P</i>=0.004) and serum ferritin [Median difference: -1091.9, <i>P</i><0.001), between survivors and non-survivors, respectively. <b>Conclusion:</b> The results revealed that some hematological and endocrine factors play an important role in prognosis of COVID-19 infection. However, further studies with a larger population are required to clarify the exact effects of COVID-19 on the endocrine system.</p>\",\"PeriodicalId\":46588,\"journal\":{\"name\":\"Health Promotion Perspectives\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2022-08-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9508391/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Health Promotion Perspectives\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.34172/hpp.2022.26\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Health Promotion Perspectives","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34172/hpp.2022.26","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
What hematological and endocrinal indicators are important in COVID-19 infection?
Background: Clinical evidence of endocrine involvement in coronavirus disease needs further investigation. The aim of the present study was to assess the relationship between hematology and endocrine parameters in coronavirus disease 2019 (COVID-19) infection. Methods: In the present cross-sectional study, a total of 320 patients (215 survivors and 105 non-survivors) with confirmed COVID-19 infection were enrolled. After isolation of serum samples, hematological, biochemical, and hormonal parameters were analyzed. Results: The mean age of survivors and non-survivors was 58.92 (SD: 15.28) and 63.65 (SD: 16.62) years, respectively. The results demonstrated significant differences in free triiodothyronine (FT3) [MD (95% CI): 0.40 (0.10, 0.71), P=0.009], total calcium [MD (95% CI): 0.53 (0.21, 0.86), P=0.003], vitamin D [MD (95% CI): 7.72 (6.38, 9.05), P=0.003], erythrocyte sedimentation rate (ESR) [MD (95% CI): 17.09 (9.38, 22.05), P=0.004) and serum ferritin [Median difference: -1091.9, P<0.001), between survivors and non-survivors, respectively. Conclusion: The results revealed that some hematological and endocrine factors play an important role in prognosis of COVID-19 infection. However, further studies with a larger population are required to clarify the exact effects of COVID-19 on the endocrine system.
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