高浓度局麻加类固醇外周阻滞治疗三叉神经痛的疗效评价。

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL
Esra Ertilav, Osman Nuri Aydın
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引用次数: 0

摘要

目的:本研究的目的是探讨外周阻滞应用高浓度局麻和类固醇治疗三叉神经痛的有效性持续时间。方法:回顾性分析48例患者(内科治疗9例,外周阻滞及Gasser神经节射频热凝介入治疗39例)的资料。在36个月的随访中,评估患者使用的药物、术前和术后视觉模拟量表评分以及手术的有效性持续时间。结果:48例患者(32名女性,16名男性)接受了原发性和继发性病因的治疗。三叉神经V1分支3例,V2分支12例,V3分支25例,V2+V3分支8例。31例患者仅行外周阻滞,8例患者外周阻滞后行Gasser神经节RFT。24例接受外周阻滞的患者,疼痛严重程度减轻≥50%,外周阻滞的平均有效时间为7.5个月。8例患者接受Gasser神经节RFT后疼痛强度减轻≥50%,平均有效时间为22.7个月(p=0.002)。虽然一例患者在RFT后出现上颚感觉减退,但没有严重的副作用记录。结论:三叉神经痛外周支阻滞的镇痛时间虽不如RFT长,但由于所使用的高浓度局麻药具有神经毒性,是一种侵入性相对较小、复杂性较低的介入技术,且疗效持续时间较好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of the effectiveness duration of peripheral blocks applied with high concentration local anesthetic and steroid in trigeminal neuralgia.

Objectives: The aim of this study was to investigate the effectiveness duration of the peripheral blocks applied with high concentration local anesthetic and steroid in trigeminal neuralgia.

Methods: The data of 48 patients (nine patients received medical treatment and 39 patients underwent interventional procedure for peripheral block and Gasser ganglion radiofrequency thermocoagulation [RFT]) were analyzed retrospectively. The medications used by patients, pre-operative and post-operative visual analog scale scores who underwent interventional procedures, and duration for effectiveness of the procedure were evaluated with 36 months follow-up.

Results: Forty-eight patients (32 females and 16 males) who were treated with primary and secondary etiologies were evaluated. Three patients V1, 12 patients V2, 25 patients V3, and eight patients V2+V3 trigeminal nerve branches described appropriate clinical symptoms. Only peripheral block was applied to 31 patients and Gasser ganglion RFT was applied to eight patients after peripheral block. In 24 patients who underwent peripheral block, pain severity reduction was ≥50%, mean effectiveness duration of peripheral block was 7.5 months. The eight patients undergoing Gasser ganglion RFT had ≥50% pain intensity reduction, mean effectiveness duration of Gasser ganglion RFT was 22.7 months (p=0.002). While one patient had hypoesthesia in the palate after RFT, no serious side effects were recorded.

Conclusion: The duration of pain control for peripheral branch blocks in trigeminal neuralgia is not as long as RFT, but it is a relatively less invasive and less complicated interventional technique with good efficacy duration due to neurotoxicity of the used high concentrated local anesthetic.

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CiteScore
1.00
自引率
16.70%
发文量
22
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