Aline Moraes da Silva , Marcos Antonio Ferreira Júnior , Andréia Insabralde de Queiroz Cardoso , Maria Lucia Ivo , Jéssica Prince Fontes Almeida , Rayane Dayara Souza Melo
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However, few studies have been developed on analyzing the costs of obtaining organs and tissues for transplants in order to support the decision-making of managers and health professionals.</p></div><div><h3>Objective</h3><p>To summarize the studies related to the cost of obtaining organs for transplants from a deceased donor.</p></div><div><h3>Method</h3><p>A systematic literature review<span> was conducted in the following databases: PubMed, Cochrane Library CINAHAL, Virtual Health Library (BVS), SCOPUS, Web of Science and EMBASE, using the following descriptors: Costs and cost analysis; Donor Selection; Tissue and Organ Procurement; Tissue and Organ Harvesting; and Tissue Donors, in studies published until April 2021. The risk of bias assessment was performed using the Joanna Briggs Institute's Checklist for Economic Assessments. It was not possible to perform a meta-analysis due to the heterogeneity of the studies.</span></p></div><div><h3>Results</h3><p>A total of 1731 studies were identified, of which 11 were analyzed. The cost of kidneys in US dollars (USD) ranged between USD $1672 and USD $25,058. Obtaining a liver ranged from USD $586 to USD $44,478. Heart procurement ranged from USD $633 to USD $24,264. The combined heart-lung transplant ranged from USD $860 to USD $23,203. Obtaining the pancreas ranged from USD $413 to USD $29,708.</p></div><div><h3>Conclusions</h3><p>Cost of obtaining organs for transplants from a deceased donor is substantial and varies widely across different studies. The overall cost of failures to obtain organs is currently unknown. Understanding organ procurement expenses can help clarify areas in which organ and tissue procurement can improve in cost and efficiency.</p></div>","PeriodicalId":48973,"journal":{"name":"Transplantation Reviews","volume":"36 4","pages":"Article 100724"},"PeriodicalIF":3.6000,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Costs related to obtaining organs for transplantation: A systematic review\",\"authors\":\"Aline Moraes da Silva , Marcos Antonio Ferreira Júnior , Andréia Insabralde de Queiroz Cardoso , Maria Lucia Ivo , Jéssica Prince Fontes Almeida , Rayane Dayara Souza Melo\",\"doi\":\"10.1016/j.trre.2022.100724\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>The number of transplants in the world is growing, although there is a demand that exceeds supply. It is worth mentioning that the costs for obtaining organs are considered high. However, few studies have been developed on analyzing the costs of obtaining organs and tissues for transplants in order to support the decision-making of managers and health professionals.</p></div><div><h3>Objective</h3><p>To summarize the studies related to the cost of obtaining organs for transplants from a deceased donor.</p></div><div><h3>Method</h3><p>A systematic literature review<span> was conducted in the following databases: PubMed, Cochrane Library CINAHAL, Virtual Health Library (BVS), SCOPUS, Web of Science and EMBASE, using the following descriptors: Costs and cost analysis; Donor Selection; Tissue and Organ Procurement; Tissue and Organ Harvesting; and Tissue Donors, in studies published until April 2021. The risk of bias assessment was performed using the Joanna Briggs Institute's Checklist for Economic Assessments. It was not possible to perform a meta-analysis due to the heterogeneity of the studies.</span></p></div><div><h3>Results</h3><p>A total of 1731 studies were identified, of which 11 were analyzed. The cost of kidneys in US dollars (USD) ranged between USD $1672 and USD $25,058. Obtaining a liver ranged from USD $586 to USD $44,478. Heart procurement ranged from USD $633 to USD $24,264. The combined heart-lung transplant ranged from USD $860 to USD $23,203. Obtaining the pancreas ranged from USD $413 to USD $29,708.</p></div><div><h3>Conclusions</h3><p>Cost of obtaining organs for transplants from a deceased donor is substantial and varies widely across different studies. The overall cost of failures to obtain organs is currently unknown. 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引用次数: 0
摘要
世界上器官移植的数量正在增长，尽管供不应求。值得一提的是，获得器官的成本被认为很高。然而，很少有研究分析获得用于移植的器官和组织的成本，以支持管理人员和卫生专业人员的决策。目的总结从死者供体获得器官移植所需费用的相关研究。方法在PubMed、Cochrane Library CINAHAL、Virtual Health Library (BVS)、SCOPUS、Web of Science和EMBASE等数据库中进行系统文献综述，采用以下描述词:成本和成本分析;供选择;组织和器官获取;组织和器官摘取;和组织捐赠者，在2021年4月之前发表的研究中。偏见风险评估使用乔安娜布里格斯研究所的经济评估清单进行。由于研究的异质性，不可能进行荟萃分析。结果共纳入1731项研究，对其中11项进行了分析。肾脏的费用按美元计算在1672美元到25,058美元之间。获得肝脏的费用从586美元到44,478美元不等。心脏采购价格从633美元到24264美元不等。联合心肺移植的费用从860美元到23203美元不等。获得胰腺的费用从413美元到29,708美元不等。从已故供者身上获得器官用于移植的成本是巨大的，并且在不同的研究中差异很大。未能获得器官的总成本目前尚不清楚。了解器官采购费用可以帮助明确器官和组织采购可以提高成本和效率的领域。
Costs related to obtaining organs for transplantation: A systematic review
Introduction
The number of transplants in the world is growing, although there is a demand that exceeds supply. It is worth mentioning that the costs for obtaining organs are considered high. However, few studies have been developed on analyzing the costs of obtaining organs and tissues for transplants in order to support the decision-making of managers and health professionals.
Objective
To summarize the studies related to the cost of obtaining organs for transplants from a deceased donor.
Method
A systematic literature review was conducted in the following databases: PubMed, Cochrane Library CINAHAL, Virtual Health Library (BVS), SCOPUS, Web of Science and EMBASE, using the following descriptors: Costs and cost analysis; Donor Selection; Tissue and Organ Procurement; Tissue and Organ Harvesting; and Tissue Donors, in studies published until April 2021. The risk of bias assessment was performed using the Joanna Briggs Institute's Checklist for Economic Assessments. It was not possible to perform a meta-analysis due to the heterogeneity of the studies.
Results
A total of 1731 studies were identified, of which 11 were analyzed. The cost of kidneys in US dollars (USD) ranged between USD $1672 and USD $25,058. Obtaining a liver ranged from USD $586 to USD $44,478. Heart procurement ranged from USD $633 to USD $24,264. The combined heart-lung transplant ranged from USD $860 to USD $23,203. Obtaining the pancreas ranged from USD $413 to USD $29,708.
Conclusions
Cost of obtaining organs for transplants from a deceased donor is substantial and varies widely across different studies. The overall cost of failures to obtain organs is currently unknown. Understanding organ procurement expenses can help clarify areas in which organ and tissue procurement can improve in cost and efficiency.
期刊介绍：
Transplantation Reviews contains state-of-the-art review articles on both clinical and experimental transplantation. The journal features invited articles by authorities in immunology, transplantation medicine and surgery.
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