68 Ga-FAPI-04在一例胆囊癌症中优于18F-FDG。

IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Nuclear Medicine and Molecular Imaging Pub Date : 2022-10-01 Epub Date: 2022-08-05 DOI:10.1007/s13139-022-00763-5
Chunmei Guo, Dengsai Peng, Ya Liu, Liming Chen, Zhanwen Huang
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引用次数: 0

摘要

一名56岁的男子出现模糊的上腹部疼痛,持续时间超过4个月。他的腹部超声和MRI显示胆囊颈部和底部增厚,胆囊底部形成结节。18F-FDG PET/CT显示胆囊底部和多个淋巴结有强烈的FDG摄取。68Ga-FAPI-04 PET/CT不仅在上述FDG狂热病变中显示出强烈的FAPI摄取,而且在胆囊的颈部病变和一些其他额外的淋巴结中显示出较强的FAPI摄入。最后,组织病理学检查证实胆囊颈部和底部的低分化管状腺癌。我们的病例表明,68 Ga-FAPI-04 PET/CT在检测胆囊癌症原发性和转移性病变方面可能优于18F-FDG PET/CT。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Superiority of 68 Ga-FAPI-04 over 18F-FDG in a Case of Gallbladder Cancer.

A 56-year-old man presented with vague upper abdominal pain for more than 4 months. His abdominal ultrasound and MRI showed thickening of the neck and base of the gallbladder and nodule formation at the base of the gallbladder. 18F-FDG PET/CT revealed intense FDG uptake in the base of the gallbladder and multiple lymph nodes. 68 Ga-FAPI-04 PET/CT not only showed intense FAPI uptake in the above mentioned FDG-avid lesions but also showed intense FAPI uptake in the neck lesion of the gallbladder and some other additional lymph nodes. Finally, histopathological examination confirmed poorly differentiated tubular adenocarcinoma of the neck and base of the gallbladder. Our case illustrated that 68 Ga-FAPI-04 PET/CT may outperform 18F-FDG PET/CT in the detection of gallbladder cancer primary and metastatic lesions.

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来源期刊
Nuclear Medicine and Molecular Imaging
Nuclear Medicine and Molecular Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
2.20
自引率
7.70%
发文量
58
期刊介绍: Nuclear Medicine and Molecular Imaging (Nucl Med Mol Imaging) is an official journal of the Korean Society of Nuclear Medicine, which bimonthly publishes papers on February, April, June, August, October, and December about nuclear medicine and related sciences such as radiochemistry, radiopharmacy, dosimetry and pharmacokinetics / pharmacodynamics of radiopharmaceuticals, nuclear and molecular imaging analysis, nuclear and molecular imaging instrumentation, radiation biology and radionuclide therapy. The journal specially welcomes works of artificial intelligence applied to nuclear medicine. The journal will also welcome original works relating to molecular imaging research such as the development of molecular imaging probes, reporter imaging assays, imaging cell trafficking, imaging endo(exo)genous gene expression, and imaging signal transduction. Nucl Med Mol Imaging publishes the following types of papers: original articles, reviews, case reports, editorials, interesting images, and letters to the editor. The Korean Society of Nuclear Medicine (KSNM) KSNM is a scientific and professional organization founded in 1961 and a member of the Korean Academy of Medical Sciences of the Korean Medical Association which was established by The Medical Services Law. The aims of KSNM are the promotion of nuclear medicine and cooperation of each member. The business of KSNM includes holding academic meetings and symposia, the publication of journals and books, planning and research of promoting science and health, and training and qualification of nuclear medicine specialists.
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