Hannah Denis, Richard Werth, Andreas Greuling, Rainer Schwestka-Polly, Meike Stiesch, Viktoria Meyer-Kobbe, Katharina Doll
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The material was characterized by energy dispersive X‑ray (EDX) analysis and roughness measurement. To test for antibacterial properties in situ, individual occlusal splints equipped with specimens were worn intraorally by 12 periodontal healthy patients for 48 h. After fluorescence staining, the quantitative biofilm volume and live/dead distribution of the initial biofilm formation were analyzed by confocal laser scanning microscopy (CLSM).</p><p><strong>Results: </strong>Silver was infiltrated homogeneously throughout the tungsten matrix. Toothbrush abrasion only slightly reduced the material's thickness similar to conventional stainless steel bracket material and did not alter surface roughness. The new silver-modified material showed significantly reduced biofilm accumulation in situ. The effect was maintained even after abrasion.</p><p><strong>Conclusion: </strong>A promising, novel silver-infiltrated abrasion-stable material for use as orthodontic brackets, which also exhibit strong antibacterial properties on in situ grown oral biofilms, was developed. The strong antibacterial properties were maintained even after surface abrasion simulated with long-term toothbrushing.</p>","PeriodicalId":54776,"journal":{"name":"Journal of Orofacial Orthopedics-Fortschritte Der Kieferorthopadie","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10791857/pdf/","citationCount":"0","resultStr":"{\"title\":\"Antibacterial properties and abrasion-stability: Development of a novel silver-compound material for orthodontic bracket application.\",\"authors\":\"Hannah Denis, Richard Werth, Andreas Greuling, Rainer Schwestka-Polly, Meike Stiesch, Viktoria Meyer-Kobbe, Katharina Doll\",\"doi\":\"10.1007/s00056-022-00405-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Bacteria-induced white spot lesions are a common side effect of modern orthodontic treatment. 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引用次数: 0
摘要
目的:细菌引起的白斑病是现代正畸治疗的常见副作用。因此,需要具有抗菌性能且能长期耐磨的新型正畸托槽材料。本研究的目的是在原位实验中研究一种新开发的、彻底渗银的正畸托槽材料的耐磨抗菌性能:为了生成这种新型材料,银被真空渗入烧结的多孔钨基体中。使用刷牙模拟机进行相当于 2 年刷牙时间的磨损。通过能量色散 X 射线(EDX)分析和粗糙度测量对材料进行了表征。为了测试原位抗菌性能,12 名牙周健康的患者在口腔内佩戴了装有试样的单个咬合夹板 48 小时。荧光染色后,通过共焦激光扫描显微镜(CLSM)分析了生物膜形成初期的定量生物膜体积和活/死分布:结果:银均匀地渗入整个钨基质。牙刷的磨损仅使材料的厚度略微减薄,与传统的不锈钢支架材料相似,并没有改变表面粗糙度。新的银改性材料显著减少了生物膜在原位的积聚。结论:结论:研究人员开发出了一种很有前景的新型渗银耐磨材料,可用作正畸托槽,并对原位生长的口腔生物膜具有很强的抗菌性能。即使在模拟长期刷牙的表面磨损后,这种材料仍能保持较强的抗菌性能。
Antibacterial properties and abrasion-stability: Development of a novel silver-compound material for orthodontic bracket application.
Purpose: Bacteria-induced white spot lesions are a common side effect of modern orthodontic treatment. Therefore, there is a need for novel orthodontic bracket materials with antibacterial properties that also resist long-term abrasion. The aim of this study was to investigate the abrasion-stable antibacterial properties of a newly developed, thoroughly silver-infiltrated material for orthodontic bracket application in an in situ experiment.
Methods: To generate the novel material, silver was vacuum-infiltrated into a sintered porous tungsten matrix. A tooth brushing simulation machine was used to perform abrasion equal to 2 years of tooth brushing. The material was characterized by energy dispersive X‑ray (EDX) analysis and roughness measurement. To test for antibacterial properties in situ, individual occlusal splints equipped with specimens were worn intraorally by 12 periodontal healthy patients for 48 h. After fluorescence staining, the quantitative biofilm volume and live/dead distribution of the initial biofilm formation were analyzed by confocal laser scanning microscopy (CLSM).
Results: Silver was infiltrated homogeneously throughout the tungsten matrix. Toothbrush abrasion only slightly reduced the material's thickness similar to conventional stainless steel bracket material and did not alter surface roughness. The new silver-modified material showed significantly reduced biofilm accumulation in situ. The effect was maintained even after abrasion.
Conclusion: A promising, novel silver-infiltrated abrasion-stable material for use as orthodontic brackets, which also exhibit strong antibacterial properties on in situ grown oral biofilms, was developed. The strong antibacterial properties were maintained even after surface abrasion simulated with long-term toothbrushing.
期刊介绍:
The Journal of Orofacial Orthopedics provides orthodontists and dentists who are also actively interested in orthodontics, whether in university clinics or private practice, with highly authoritative and up-to-date information based on experimental and clinical research. The journal is one of the leading publications for the promulgation of the results of original work both in the areas of scientific and clinical orthodontics and related areas. All articles undergo peer review before publication. The German Society of Orthodontics (DGKFO) also publishes in the journal important communications, statements and announcements.