WHO CNS5 2021神经胶质瘤的分类:一个实用的回顾和道路标志诊断病理学家和适当的病理临床和神经肿瘤学合作。

IF 1.5 4区医学 Q4 NEUROSCIENCES

Folia neuropathologica Pub Date : 2022-01-01 DOI:10.5114/fn.2022.118183

Aleksandra Sejda, Wiesława Grajkowska, Joanna Trubicka, Ewa Szutowicz, Tomasz Wojdacz, Wojciech Kloc, Ewa Iżycka-Świeszewska

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引用次数: 8

摘要

世界卫生组织(WHO)第五版中枢神经系统(CNS)肿瘤分类将胶质瘤的病理诊断从纯粹的组织学转变为具有分子生物标志物的多层综合诊断，以进行适当的分类，风险分层和预后预测临床目的。由于神经胶质瘤的分类和诊断方法发生了深刻而重要的变化，本手稿是WHO CNS分类第5版的综述，为神经肿瘤学病理学家和临床医生提供一般测试指南。

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WHO CNS5 2021 classification of gliomas: a practical review and road signs for diagnosing pathologists and proper patho-clinical and neuro-oncological cooperation.

The 5th edition of World Health Organization (WHO) Central Nervous System (CNS) tumours classification has transformed the pathological diagnosis of gliomas from purely histological to the multilayered integrated one with molecular biomarkers necessary for proper classification, risk stratification, and prognostic-predictive clinical purposes. Because of deep and important changes in taxonomy and diagnostic approach to gliomas, this manuscript is a review of WHO CNS classification 5th edition with general testing guidance for pathologists and clinicians working in neuro-oncology.

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来源期刊

Folia neuropathologica 医学-病理学

CiteScore

2.50

自引率

5.00%

发文量

审稿时长

>12 weeks

期刊介绍： Folia Neuropathologica is an official journal of the Mossakowski Medical Research Centre Polish Academy of Sciences and the Polish Association of Neuropathologists. The journal publishes original articles and reviews that deal with all aspects of clinical and experimental neuropathology and related fields of neuroscience research. The scope of journal includes surgical and experimental pathomorphology, ultrastructure, immunohistochemistry, biochemistry and molecular biology of the nervous tissue. Papers on surgical neuropathology and neuroimaging are also welcome. The reports in other fields relevant to the understanding of human neuropathology might be considered.