簇状细胞:肠粘膜的哨兵。

IF 0.7 4区生物学 Q4 BIOLOGY

Comptes Rendus Biologies Pub Date : 2021-11-15 DOI:10.5802/crbiol.60

Philippe Jay

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引用次数: 0

摘要

肠上皮是我们与外界包括肠道微生物群的主要接口之一。因此，这种上皮结合了营养吸收和屏障两种基本功能。肠上皮由几种特化的细胞类型组成，以实现其不同的功能。其中，簇状细胞长期以来一直处于阴影之中，但近年来对其功能的理解急剧加快。本文综述了肠粘膜簇状细胞的特征及其前哨功能的发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Tuft cells: sentinels of the intestinal mucosa.

The intestinal epithelium is one of our main interfaces with the outside world, including the intestinal microbiota. This epithelium thus combines the two essential functions of nutrient absorption and barrier. In order to fulfill its different roles, the intestinal epithelium is made up of several specialized cell types. Among these, tuft cells have long remained in the shadows, but the understanding of their function has accelerated dramatically in recent years. The purpose of this review is to outline the characterization of tuft cells and the discovery of their sentinel function in the intestinal mucosa.

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来源期刊

Comptes Rendus Biologies 生物-生物学

CiteScore

2.40

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： The Comptes rendus Biologies publish monthly communications dealing with all biological and medical research fields (biological modelling, development and reproduction biology, cell biology, biochemistry, neurosciences, immunology, pharmacology, ecology, etc.). Articles are preferably written in English. Articles in French with an abstract in English are accepted.