{"title":"医院源性COVID-19:法国一所大学医院首次出现SARS-CoV-2 B.1.1.7变体的院内传播，说明了这一风险。","authors":"Clément Legeay, Caroline Lefeuvre","doi":"10.1177/17571774221127543","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>In this short report, we describe the first nosocomial spread of B.1.1.7 variant (GR/20I/501Y.V1) in a French hospital, underlining the different aspects of in-hospital transmission of SARS-CoV-2.</p><p><strong>Patients and methods: </strong>Retrospective study of a SARS-CoV-2 cluster investigation in January 2021. All cases were screened with RT-PCR.</p><p><strong>Results: </strong>First transmission occurred in a double room with a COVID-19 imported cases, undetected upon admission. Healthcare workers, their relatives and patients' relatives were screened. Eleven secondary cases were identified within a week, in and out of the hospital (in hospital attack rate: 3.1%). No severe COVID-19 was encountered.</p><p><strong>Conclusions: </strong>This report highlights several in-hospital chains of transmission involved with COVID-19 with rapid spread.</p>","PeriodicalId":0,"journal":{"name":"","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475369/pdf/","citationCount":"1","resultStr":"{\"title\":\"Nosocomial COVID-19, a risk illustrated by the first in-hospital transmission of B.1.1.7 variant of SARS-CoV-2 in a French University Hospital.\",\"authors\":\"Clément Legeay, Caroline Lefeuvre\",\"doi\":\"10.1177/17571774221127543\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>In this short report, we describe the first nosocomial spread of B.1.1.7 variant (GR/20I/501Y.V1) in a French hospital, underlining the different aspects of in-hospital transmission of SARS-CoV-2.</p><p><strong>Patients and methods: </strong>Retrospective study of a SARS-CoV-2 cluster investigation in January 2021. All cases were screened with RT-PCR.</p><p><strong>Results: </strong>First transmission occurred in a double room with a COVID-19 imported cases, undetected upon admission. Healthcare workers, their relatives and patients' relatives were screened. Eleven secondary cases were identified within a week, in and out of the hospital (in hospital attack rate: 3.1%). No severe COVID-19 was encountered.</p><p><strong>Conclusions: </strong>This report highlights several in-hospital chains of transmission involved with COVID-19 with rapid spread.</p>\",\"PeriodicalId\":0,\"journal\":{\"name\":\"\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0,\"publicationDate\":\"2022-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9475369/pdf/\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/17571774221127543\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/9/14 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/17571774221127543","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/9/14 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Nosocomial COVID-19, a risk illustrated by the first in-hospital transmission of B.1.1.7 variant of SARS-CoV-2 in a French University Hospital.
Objectives: In this short report, we describe the first nosocomial spread of B.1.1.7 variant (GR/20I/501Y.V1) in a French hospital, underlining the different aspects of in-hospital transmission of SARS-CoV-2.
Patients and methods: Retrospective study of a SARS-CoV-2 cluster investigation in January 2021. All cases were screened with RT-PCR.
Results: First transmission occurred in a double room with a COVID-19 imported cases, undetected upon admission. Healthcare workers, their relatives and patients' relatives were screened. Eleven secondary cases were identified within a week, in and out of the hospital (in hospital attack rate: 3.1%). No severe COVID-19 was encountered.
Conclusions: This report highlights several in-hospital chains of transmission involved with COVID-19 with rapid spread.
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