[安第斯儿童动脉瘤性骨囊肿用聚多坎醇治疗(说明书外使用)]。

Acta ortopedica mexicana Pub Date : 2021-11-01
R E Ríos-Méndez, L G Espin-Villamarin, C J Rovalino-Troya, V F Rosero-Lema, E B Barona-Freire, D I Reinoso-Recalde
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摘要

动脉瘤性骨囊肿是一种罕见的良性但侵袭性的溶骨性肿瘤,目前尚无理想的治疗方法,在小儿人群中应用硬化疗法治疗的报道很少,在我国地区更是少之又少。目的是探讨3%聚多酚治疗动脉瘤性骨囊肿的经验。材料方法:回顾性、描述性和横断面研究。。期间:2017年6月至2021年6月。纳入:组织学诊断为动脉瘤性骨囊肿的患者;全麻下透视引导下,用16G针穿刺局内,缓慢给药3%聚多卡因。资料:病史。定量变量应以集中趋势和离散度表示;定性变量应以频率或百分比表示。结果:连续纳入9例患者,均有一侧肢体疼痛和肿瘤。性别:女性3人,男性6人。年龄:中位10.5岁(范围:2-15.1)。体重:中位数32.8 kg(范围:11-44.5)。总程序:44;每位患者手术次数:平均4.9次(SD:±2.0)。手术时间:平均33.9分钟(SD:±18.3);辐射:平均1.34 mGy (SD:±1.55)。住院:一天,除一名患者。并发症:1例皮肤损伤,无复发,随访12 ~ 50个月。结论:在这个儿科系列中,3%聚多酚治疗动脉瘤性骨囊肿是有用和有效的,且并发症少。一个缺点是它需要多次治疗,此外,在复发率方面,其他形式的治疗之间没有显着差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Andean children with aneurysmal bone cyst treated with polidocanol (use off-label)].

Introduction: The aneurysmal bone cyst is a rare benign but aggressive osteolytic tumor for which there is still no ideal treatment, the reports on treatment by sclerotherapy in the pediatric population are scarce and in our region even less. The objective is to communicate the experience of the treatment of aneurysmal bone cyst with polydocanol 3%.

Material y methods: Retrospective, descriptive and cross-sectional study. Period: June/2017 to June/2021. Inclusion: patients with histological diagnosis of aneurysmal bone cyst; Under general anesthesia and fluoroscopic guidance, intralesional puncture with 16G needle was performed through which 3% polydocanol was slowly administered. Data: medical history. Quantitative variables shall be expressed in measures of central tendency and dispersion; qualitative variables shall be expressed as frequencies or percentages.

Results: Nine consecutive patients were included, all of whom had pain and tumor in one of the extremities. Gender: 3 female and 6 male. Age: median 10.5 years (range: 2-15.1). Weight: median 32.8 kg (range: 11-44.5). Total procedures: 44; procedures per patient: mean 4.9 (SD: ± 2.0). Procedure time: mean 33.9 minutes (SD: ± 18.3); radiation: mean 1.34 mGy (SD: ± 1.55). Hospitalization: one day, except one patient. Complications: skin damage in one case, no recurrences follow-up: 12 to 50 months.

Conclusion: In this pediatric series, polydocanol 3% was useful and effective for the treatment of aneurysmal bone cyst, with few complications. One disadvantage is that it requires several sessions and in addition, no significant difference has been demonstrated between other forms of treatment in terms of the recurrence rate.

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