{"title":"在巴马科rodolpher - m<s:1> rieux实验室，通过糖化血红蛋白检测D-10®(Biorad)和Minicap Flex穿刺®(Sebia)生化系统监测血糖平衡","authors":"Aboubacar Dit Tietie Bissan, Casimir Kletigui Dembélé, Djibril Coulibaly, Yaya Goïta, Djambatolom Saidou Tolo, Boubacar Mohammed, Asmaou Soumaré, Madiné Tall, Lassana Gadi Timbiné, Bakary Cissé, Bourèma Kouriba","doi":"10.1684/abc.2022.1738","DOIUrl":null,"url":null,"abstract":"<p><p>This study aims to determine the concordance of results between D-10® and Minicap Flex Piercing® and the impact of the presence of hemoglobin variants in the glycated hemoglobin assay. All the samples were assayed in parallel. The agreement between these methods was assessed using the Bland and Altman plot. We collected a total of 166 samples. In the entire study population and in patients with a hemoglobin variant, the Bland and Altman graph showed good agreement between the values (for respective biases of 0.21% and 0.29%) as well as a significant correlation (p < 0.001). Our results differ from those found by Kesso Barry et al. This difference can be explained by the high prevalence of patients with abnormal hemoglobins S and C (39.2 %) in our study population. Despite a good agreement between the methods, the results do not allow us to confirm a transferability between the two systems in diabetics and carriers of hemoglobin variants.</p>","PeriodicalId":7892,"journal":{"name":"Annales de biologie clinique","volume":null,"pages":null},"PeriodicalIF":0.4000,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Monitoring of glycemic balance by glycated hemoglobin assay on D-10® (Biorad) and Minicap Flex Piercing® (Sebia) biochemical systems at the Rodolph-Mérieux Laboratory in Bamako\",\"authors\":\"Aboubacar Dit Tietie Bissan, Casimir Kletigui Dembélé, Djibril Coulibaly, Yaya Goïta, Djambatolom Saidou Tolo, Boubacar Mohammed, Asmaou Soumaré, Madiné Tall, Lassana Gadi Timbiné, Bakary Cissé, Bourèma Kouriba\",\"doi\":\"10.1684/abc.2022.1738\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study aims to determine the concordance of results between D-10® and Minicap Flex Piercing® and the impact of the presence of hemoglobin variants in the glycated hemoglobin assay. All the samples were assayed in parallel. The agreement between these methods was assessed using the Bland and Altman plot. We collected a total of 166 samples. In the entire study population and in patients with a hemoglobin variant, the Bland and Altman graph showed good agreement between the values (for respective biases of 0.21% and 0.29%) as well as a significant correlation (p < 0.001). Our results differ from those found by Kesso Barry et al. This difference can be explained by the high prevalence of patients with abnormal hemoglobins S and C (39.2 %) in our study population. Despite a good agreement between the methods, the results do not allow us to confirm a transferability between the two systems in diabetics and carriers of hemoglobin variants.</p>\",\"PeriodicalId\":7892,\"journal\":{\"name\":\"Annales de biologie clinique\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.4000,\"publicationDate\":\"2022-06-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annales de biologie clinique\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1684/abc.2022.1738\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICAL LABORATORY TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annales de biologie clinique","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1684/abc.2022.1738","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
Monitoring of glycemic balance by glycated hemoglobin assay on D-10® (Biorad) and Minicap Flex Piercing® (Sebia) biochemical systems at the Rodolph-Mérieux Laboratory in Bamako
This study aims to determine the concordance of results between D-10® and Minicap Flex Piercing® and the impact of the presence of hemoglobin variants in the glycated hemoglobin assay. All the samples were assayed in parallel. The agreement between these methods was assessed using the Bland and Altman plot. We collected a total of 166 samples. In the entire study population and in patients with a hemoglobin variant, the Bland and Altman graph showed good agreement between the values (for respective biases of 0.21% and 0.29%) as well as a significant correlation (p < 0.001). Our results differ from those found by Kesso Barry et al. This difference can be explained by the high prevalence of patients with abnormal hemoglobins S and C (39.2 %) in our study population. Despite a good agreement between the methods, the results do not allow us to confirm a transferability between the two systems in diabetics and carriers of hemoglobin variants.
期刊介绍：
Multidisciplinary information with direct relevance to everyday practice
Annales de Biologie Clinique, the official journal of the French Society of Clinical Biology (SFBC), supports biologists in areas including continuing education, laboratory accreditation and technique validation.
With original articles, abstracts and accounts of everyday practice, the journal provides details of advances in knowledge, techniques and equipment, as well as a forum for discussion open to the entire community.
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