Paul L Carmichael, Maria T Baltazar, Sophie Cable, Stella Cochrane, Matthew Dent, Hequn Li, Alistair Middleton, Iris Muller, Georgia Reynolds, Carl Westmoreland, Andrew White
{"title":"准备用于监管:NAMs和NGRA用于化学安全保证。","authors":"Paul L Carmichael, Maria T Baltazar, Sophie Cable, Stella Cochrane, Matthew Dent, Hequn Li, Alistair Middleton, Iris Muller, Georgia Reynolds, Carl Westmoreland, Andrew White","doi":"10.14573/altex.2204281","DOIUrl":null,"url":null,"abstract":"<p><p>New approach methodologies (NAMs) that do not use experimental animals are, in certain settings, entirely appropriate for assuring the safety of chemical ingredients, although regulatory adoption has been slow. In this opinion article we discuss how scientific advances that utilize NAMs to certify systemic safety are available now and merit broader acceptance within the framework of next generation risk assessments (NGRA).</p>","PeriodicalId":520550,"journal":{"name":"ALTEX","volume":" ","pages":"359–366"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"16","resultStr":"{\"title\":\"Ready for regulatory use: NAMs and NGRA for chemical safety assurance.\",\"authors\":\"Paul L Carmichael, Maria T Baltazar, Sophie Cable, Stella Cochrane, Matthew Dent, Hequn Li, Alistair Middleton, Iris Muller, Georgia Reynolds, Carl Westmoreland, Andrew White\",\"doi\":\"10.14573/altex.2204281\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>New approach methodologies (NAMs) that do not use experimental animals are, in certain settings, entirely appropriate for assuring the safety of chemical ingredients, although regulatory adoption has been slow. In this opinion article we discuss how scientific advances that utilize NAMs to certify systemic safety are available now and merit broader acceptance within the framework of next generation risk assessments (NGRA).</p>\",\"PeriodicalId\":520550,\"journal\":{\"name\":\"ALTEX\",\"volume\":\" \",\"pages\":\"359–366\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"16\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"ALTEX\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.14573/altex.2204281\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/7/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"ALTEX","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.14573/altex.2204281","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/7/4 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Ready for regulatory use: NAMs and NGRA for chemical safety assurance.
New approach methodologies (NAMs) that do not use experimental animals are, in certain settings, entirely appropriate for assuring the safety of chemical ingredients, although regulatory adoption has been slow. In this opinion article we discuss how scientific advances that utilize NAMs to certify systemic safety are available now and merit broader acceptance within the framework of next generation risk assessments (NGRA).
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
