COVID-19危重症患者可能的朝日毛孢丝状体尿路感染

IF 1.5 4区 生物学 Q4 MYCOLOGY
Marco Vianello , Daniel F.F. de Jesus , Jorge M. Sampaio , Guilherme M. de Oliveira , Nilton Lincopan , Kelly Ishida
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引用次数: 0

摘要

背景:朝日毛磷霉是一种新兴的真菌病原体,常与危重患者的侵袭性感染有关。病例报告一名74岁的男性患者被诊断为COVID-19,并被送入重症监护病房(ICU)。住院期间,患者出现溶血葡萄球菌引起的菌血症发作,并可能出现asahi t尿路感染。虽然使用广谱抗生素成功治疗了细菌感染,但尿路真菌感染无法用阿尼杜冯宁治疗,并持续到患者死亡。结论随着COVID-19大流行的发展,侵袭性真菌感染的报道越来越多,主要是在长期服用免疫抑制药物和广谱抗生素治疗后。虽然念珠菌和曲霉菌仍然是最普遍的侵袭性真菌,但朝日弧菌和其他病原体已经出现在危重患者中。因此,适当监测和诊断任何真菌感染至关重要,特别是在COVID-19免疫功能低下人群中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Possible Trichosporon asahii urinary tract infection in a critically ill COVID-19 patient

Possible Trichosporon asahii urinary tract infection in a critically ill COVID-19 patient

Background

Trichosporon asahii, an emerging fungal pathogen, has been frequently associated with invasive infections in critically ill patients.

Case report

A 74-year-old male patient diagnosed with COVID-19 was admitted to an Intensive Care Unit (ICU). During hospitalization, the patient displayed episodes of bacteremia by Staphylococcus haemolyticus and a possible urinary tract infection by T. asahii. While the bacterial infection was successfully treated using broad-spectrum antibiotics, the fungal infection in the urinary tract was unsuccessfully treated with anidulafungin and persisted until the patient died.

Conclusions

With the evolving COVID-19 pandemic, invasive fungal infections have been increasingly reported, mainly after taking immunosuppressant drugs associated with long-term broad-spectrum antibiotic therapy. Although Candida and Aspergillus are still the most prevalent invasive fungi, T. asahii and other agents have emerged in critically ill patients. Therefore, a proper surveillance and diagnosing any fungal infection are paramount, particularly in COVID-19 immunocompromised populations.

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来源期刊
CiteScore
1.90
自引率
0.00%
发文量
17
审稿时长
81 days
期刊介绍: Revista Iberoamericana de Micología (Ibero-American Journal of Mycology) is the official journal of the Asociación Española de Micología, Asociación Venezolana de Micología and Asociación Argentina de Micología (The Spanish, Venezuelan, and Argentinian Mycology Associations). The Journal gives priority to publishing articles on studies associated with fungi and their pathogenic action on humans and animals, as well as any scientific studies on any aspect of mycology. The Journal also publishes, in Spanish and in English, original articles, reviews, mycology forums, editorials, special articles, notes, and letters to the editor, that have previously gone through a scientific peer review process.
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