Shikha Choubey, Amol Patil, Abhinav L Talekar, Dheeraj Kalra
{"title":"纳米氟化银作为儿童防龋剂:系统回顾和荟萃分析。","authors":"Shikha Choubey, Amol Patil, Abhinav L Talekar, Dheeraj Kalra","doi":"10.4103/jisppd.jisppd_224_22","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Dental caries is one of the most common concerns in oral health of children. Arresting these lesions is a treatment which is gaining momentum as against conventional restorative approaches.</p><p><strong>Aim: </strong>The aim is to evaluate the efficacy of nanosilver fluoride (NSF) as a caries arresting agent in primary teeth or first permanent molars in children.</p><p><strong>Design: </strong>The protocol for the systematic review has been registered with PROSPERO database (CRD42020162386). Several databases, such as PubMed®/MEDLINE, Web of Science™, Scopus®, Google Scholar, LILACS, Cochrane Library, ProQuest, and BBO, were searched for randomized controlled trials (RCTs) which evaluated the arrestment of caries, in primary teeth and first permanent molars in children, with a minimum follow-up of 6 months. The Risk of Bias tool by Cochrane reviews system software, Revman 5.4.1, was used for quality assessment of the included RCTs. The quality evaluation was done using the GRADE approach. Heterogeneity was assessed using Cochrane's Q and I<sup>2</sup> statistics.</p><p><strong>Results: </strong>Five studies were included for qualitative and quantitative analysis. The Risk Ratio for NSF versus active control group was assessed to be 1.09 (0.93-1.28) with 95% Confidence Interval and for placebo control was 0.49 (0.35-0.67).</p><p><strong>Conclusion: </strong>NSF shows promise as a caries arrestment agent when applied in primary teeth.</p><p><strong>Prospero registration: </strong>This review was registered with the PROSPERO database (CRD42020162386).</p>","PeriodicalId":35797,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":" ","pages":"230-238"},"PeriodicalIF":0.0000,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nanosilver fluoride as a caries arresting agent in children: A systematic review and meta- analysis.\",\"authors\":\"Shikha Choubey, Amol Patil, Abhinav L Talekar, Dheeraj Kalra\",\"doi\":\"10.4103/jisppd.jisppd_224_22\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Dental caries is one of the most common concerns in oral health of children. Arresting these lesions is a treatment which is gaining momentum as against conventional restorative approaches.</p><p><strong>Aim: </strong>The aim is to evaluate the efficacy of nanosilver fluoride (NSF) as a caries arresting agent in primary teeth or first permanent molars in children.</p><p><strong>Design: </strong>The protocol for the systematic review has been registered with PROSPERO database (CRD42020162386). Several databases, such as PubMed®/MEDLINE, Web of Science™, Scopus®, Google Scholar, LILACS, Cochrane Library, ProQuest, and BBO, were searched for randomized controlled trials (RCTs) which evaluated the arrestment of caries, in primary teeth and first permanent molars in children, with a minimum follow-up of 6 months. The Risk of Bias tool by Cochrane reviews system software, Revman 5.4.1, was used for quality assessment of the included RCTs. The quality evaluation was done using the GRADE approach. Heterogeneity was assessed using Cochrane's Q and I<sup>2</sup> statistics.</p><p><strong>Results: </strong>Five studies were included for qualitative and quantitative analysis. The Risk Ratio for NSF versus active control group was assessed to be 1.09 (0.93-1.28) with 95% Confidence Interval and for placebo control was 0.49 (0.35-0.67).</p><p><strong>Conclusion: </strong>NSF shows promise as a caries arrestment agent when applied in primary teeth.</p><p><strong>Prospero registration: </strong>This review was registered with the PROSPERO database (CRD42020162386).</p>\",\"PeriodicalId\":35797,\"journal\":{\"name\":\"Journal of the Indian Society of Pedodontics and Preventive Dentistry\",\"volume\":\" \",\"pages\":\"230-238\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of the Indian Society of Pedodontics and Preventive Dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jisppd.jisppd_224_22\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Dentistry\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jisppd.jisppd_224_22","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Dentistry","Score":null,"Total":0}
引用次数: 0
摘要
背景:龋齿是儿童口腔健康中最常见的问题之一。与传统的恢复性方法相比，阻止这些病变是一种获得势头的治疗方法。目的:评价纳米氟化银(NSF)作为儿童乳牙和第一恒磨牙阻龋剂的疗效。设计:系统评价方案已在PROSPERO数据库注册(CRD42020162386)。检索PubMed®/MEDLINE、Web of Science™、Scopus®、Google Scholar、LILACS、Cochrane Library、ProQuest和BBO等数据库，检索评估儿童乳牙和第一恒磨牙龋齿抑制的随机对照试验(rct)，随访时间至少为6个月。采用Cochrane评价系统软件Revman 5.4.1的偏倚风险工具对纳入的随机对照试验进行质量评价。质量评价采用GRADE方法。采用Cochrane's Q和I2统计来评估异质性。结果:纳入5项研究进行定性和定量分析。NSF组与积极对照组的风险比评估为1.09(0.93-1.28)，95%可信区间，安慰剂对照组的风险比评估为0.49(0.35-0.67)。结论:NSF作为阻龋剂应用于乳牙具有良好的应用前景。普洛斯彼罗注册:本综述已在普洛斯彼罗数据库注册(CRD42020162386)。
Nanosilver fluoride as a caries arresting agent in children: A systematic review and meta- analysis.
Background: Dental caries is one of the most common concerns in oral health of children. Arresting these lesions is a treatment which is gaining momentum as against conventional restorative approaches.
Aim: The aim is to evaluate the efficacy of nanosilver fluoride (NSF) as a caries arresting agent in primary teeth or first permanent molars in children.
Design: The protocol for the systematic review has been registered with PROSPERO database (CRD42020162386). Several databases, such as PubMed®/MEDLINE, Web of Science™, Scopus®, Google Scholar, LILACS, Cochrane Library, ProQuest, and BBO, were searched for randomized controlled trials (RCTs) which evaluated the arrestment of caries, in primary teeth and first permanent molars in children, with a minimum follow-up of 6 months. The Risk of Bias tool by Cochrane reviews system software, Revman 5.4.1, was used for quality assessment of the included RCTs. The quality evaluation was done using the GRADE approach. Heterogeneity was assessed using Cochrane's Q and I2 statistics.
Results: Five studies were included for qualitative and quantitative analysis. The Risk Ratio for NSF versus active control group was assessed to be 1.09 (0.93-1.28) with 95% Confidence Interval and for placebo control was 0.49 (0.35-0.67).
Conclusion: NSF shows promise as a caries arrestment agent when applied in primary teeth.
Prospero registration: This review was registered with the PROSPERO database (CRD42020162386).
期刊介绍：
Journal of Indian Society of Pedodontics and Preventive Dentistry (ISSN - 0970-4388) is the official organ of Indian Society of Pedodontics and Preventive Dentistry. The journal publishes original articles and case reports pertaining to pediatric and preventive dentistry.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
