用于预防全喉切除术后咽峡瘘的甲状腺瓣

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY
Accounts of Chemical Research Pub Date : 2025-07-01 Epub Date: 2022-09-01 DOI:10.1177/01455613221124774
Bokhyun Song, Ye-Jin Suh, Tae Hwan Kim, Young-Ik Son, Nayeon Choi
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引用次数: 0

摘要

目的:喉瘘(PCF)是全喉切除术(TL)后的主要并发症之一,可导致唾液渗漏、大血管破裂和住院时间延长。为了防止全喉切除术中出现 PCF,人们已经尝试了多种皮瓣,但这些皮瓣通常与供体部位的发病率有关,而且之前接受过放射治疗的患者的皮瓣存活率也不确定。本研究旨在报告一种新颖的双侧带蒂甲状腺皮瓣(TGF)技术,以精细有效地加固TL术后的新咽缝线:方法:双侧带蒂甲状腺皮瓣用于TL术后新咽部T形缝线部位的加固:结果:TL期间共进行了5例TGF手术,其中4例为化疗(CRT)后的挽救性手术。所有患者的术后计算机断层扫描和甲状腺激素水平均正常。没有术后感染、出血、甲状腺功能减退、甲状旁腺功能减退或PCF的报道:结论:TGF是一种有效、可靠的TL修补皮瓣,应被视为新咽部重建的一种方法,即使是先行CRT后的抢救性TL也不例外。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Thyroid Gland Flap for Prevention of Pharyngocutaneous Fistula After Total Laryngectomy.

ObjectivesPharyngocutaneous fistula (PCF) is the one of the major complications after total laryngectomy (TL), which can result in saliva leakage, rupture of major vessels, and increased hospitalization. Several flaps have been tried to prevent PCF during TL, and they are usually associated with donor site morbidity and uncertain viability in case of previously irradiated patients. This study aimed to report a novel bilateral pedicled thyroid gland flap (TGF) technique for delicate and effective reinforcement of neopharynx suture line after TL.MethodsBilateral pedicled TGF was performed for the reinforcement of neopharynx T-shape suture sites after TL in this case series.ResultsA total of five cases of the TGF were performed during TL, with four of them being salvage setting following previous chemoradiation therapy (CRT). The well-adapted and viable TGF status was confirmed by post-operative computed tomography scan and normally preserved thyroid hormone levels in all patients. No post-operative infections, hemorrhage, hypothyroidism, hypoparathyroidism, or PCF were reported.ConclusionThe TGF is an effective and reliable flap in TL patents and should be considered as a method in neopharynx reconstruction, even in salvage TL following prior CRT.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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