食道结节病:病例回顾及最新进展。

ISRN gastroenterology Pub Date : 2013-01-01 Epub Date: 2013-03-05 DOI:10.1155/2013/836203
Albin Abraham, Rabab Hajar, Ravi Virdi, Jaspreet Singh, Paul Mustacchia
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引用次数: 22

摘要

结节病是一种慢性疾病,几乎可以影响身体的任何器官系统。组织学上,它的特点是存在T淋巴细胞,单核吞噬细胞和非干酪化肉芽肿。最常受影响的是胸内结构,90%的报告病例涉及肺部。结节病累及食管极为罕见。吞咽困难是这些患者中最常见的症状,可归因于多种机制,如食管壁直接浸润、外源性压迫、颅神经病变和脑干受累。一项全面的在线文献综述显示,结节病仅报告了23例食管受累病例。本文回顾了这些报告的病例,并详细介绍了新的诊断和治疗方案,包括未来治疗的方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Esophageal sarcoidosis: a review of cases and an update.

Sarcoidosis is a chronic disorder that can virtually affect any organ system in the body. Histologically, it is characterized by the presence of T lymphocytes, mononuclear phagocytes, and noncaseating granulomas. Most commonly affected are the intrathoracic structures, with 90% of the reported cases involving the lungs. Esophageal involvement in sarcoidosis is extremely rare. Dysphagia is the most common presentation in these patients and can be attributed to various mechanisms such as direct esophageal wall infiltration, extrinsic compression, cranial neuropathy, and brainstem involvement. A thorough online literature review revealed only 23 reported cases of esophageal involvement in sarcoidosis. This paper reviews these reported cases in detail along with newer diagnostic and treatment options, including direction of future therapy.

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