头颈部坏死性筋膜炎。

Head & Neck Pub Date : 2010-12-01 DOI:10.1002/hed.21367
Henning Wolf, Maria Rusan, Karin Lambertsen, Therese Ovesen
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引用次数: 63

摘要

背景:头颈部坏死性筋膜炎是一种进展迅速且危及生命的疾病。本研究的目的是描述患者的临床表现,微生物学,治疗和预后的重点。患者及结果:17例(男性10例;中位年龄为54岁)。9例患者在坏死性筋膜炎之前立即接受了小的头颈部手术。典型的病程是迅速扩散的红斑,明显的压痛和剧烈的疼痛。影像学显示软组织弥漫性肿胀,低分化的脂肪层扩张,皮下气体。所有患者均在2天内行手术清创,并给予广谱抗生素和血流动力学支持、高压氧和免疫球蛋白。所有患者都存活了下来,尽管17人中有12人有后遗症。结论:早期诊断至关重要。迅速蔓延的红斑和患处的极度疼痛是危险信号。采用目前的强化多模式治疗方案,死亡率为零,尽管70%有后遗症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Necrotizing fasciitis of the head and neck.

Background: Necrotizing fasciitis of the head and neck is a rapidly progressing and life-threatening condition. The purpose of this study was to describe the patients with a focus on clinical presentation, microbiology, treatment, and prognosis.

Patients and results: Seventeen patients (10 men; median age, 54 years) were included. Nine patients underwent minor head and neck surgery immediately prior to necrotizing fasciitis. The typical course was a quickly spreading erythema, pronounced tenderness, and severe pain. Imaging demonstrated diffuse swelling of the soft tissue, poorly differentiated dilated fat layers, and subcutaneous gas. All patients underwent surgical debridement within 2 days, and received broad-spectrum antibiotics and hemodynamic support, hyperbaric oxygen, and immunoglobulin. All patients survived, although 12 of 17 suffered sequelae.

Conclusions: Early diagnosis is of utmost importance. Quickly spreading erythema and extreme pain in the affected area serve as red flags. With the current intensive multimodality regimen, the mortality was zero, although 70% suffered sequelae.

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