99mTc-(V)DMSA在检测肿瘤细胞增殖中的作用。

Analytical Chemistry Insights Pub Date : 2007-12-13
Fatma Al-Saeedi
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引用次数: 0

摘要

五价锝-99m二巯基琥珀酸((99m)Tc-(V)DMSA)是一种肿瘤寻找剂,被引入到多种癌症的评估、成像和治疗中。本文综述了该制剂的起源和最新应用情况。报道了(99m)Tc-(V)DMSA与肿瘤细胞检测和增殖的关系,并描述了肿瘤细胞摄取(99m)Tc-(V)DMSA的几种机制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of 99mTc-(V)DMSA in detecting tumor cell proliferation.

Pentavalent technetium-99m dimercaptosuccinic acid ((99m)Tc-(V)DMSA) is a tumor-seeking agent which was introduced to evaluate, image, and manage many types of cancers. In this review, the beginning of, and the most recent applications of using this agent was appraised. The relation with tumor cell detection and proliferation was reported and several mechanisms of uptake of (99m)Tc-(V)DMSA in tumor cells are described.

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