{"title":"中风的感染原因","authors":"Sireesha Murala MBBS , Elanagan Nagarajan MD , Pradeep C. Bollu MD","doi":"10.1016/j.jstrokecerebrovasdis.2021.106274","DOIUrl":null,"url":null,"abstract":"<div><p><span><span><span>Stroke is one of the primary causes of mortality and morbidity worldwide. It can be ischemic or hemorrhagic, and the former can be due to an in-situ thrombus or a distant </span>embolus<span>. Despite being a rare cause, stroke can also be caused in the setting of infection. Bacterial agents are the most common cause of stroke, among other infectious agents. Until the antibiotic era, rheumatic heart disease was a predisposing risk factor of </span></span>infective endocarditis<span><span>. VZV is the most common cause of strokes in </span>pediatric and adult populations. </span></span><em>Cryptococcus</em> and <em>Candida</em><span><span><span> spp are the most common yeasts involved in CNS infections<span>, especially in immunocompromised patients. In COVID-19 patients, </span></span>ischemic strokes are more common than </span>hemorrhagic strokes. In this review, we will discuss the most common infectious agents, with particular emphasis on COVID-19.</span></p></div>","PeriodicalId":54368,"journal":{"name":"Journal of Stroke & Cerebrovascular Diseases","volume":"31 4","pages":"Article 106274"},"PeriodicalIF":2.0000,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Infectious Causes of Stroke\",\"authors\":\"Sireesha Murala MBBS , Elanagan Nagarajan MD , Pradeep C. Bollu MD\",\"doi\":\"10.1016/j.jstrokecerebrovasdis.2021.106274\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p><span><span><span>Stroke is one of the primary causes of mortality and morbidity worldwide. It can be ischemic or hemorrhagic, and the former can be due to an in-situ thrombus or a distant </span>embolus<span>. Despite being a rare cause, stroke can also be caused in the setting of infection. Bacterial agents are the most common cause of stroke, among other infectious agents. Until the antibiotic era, rheumatic heart disease was a predisposing risk factor of </span></span>infective endocarditis<span><span>. VZV is the most common cause of strokes in </span>pediatric and adult populations. </span></span><em>Cryptococcus</em> and <em>Candida</em><span><span><span> spp are the most common yeasts involved in CNS infections<span>, especially in immunocompromised patients. In COVID-19 patients, </span></span>ischemic strokes are more common than </span>hemorrhagic strokes. In this review, we will discuss the most common infectious agents, with particular emphasis on COVID-19.</span></p></div>\",\"PeriodicalId\":54368,\"journal\":{\"name\":\"Journal of Stroke & Cerebrovascular Diseases\",\"volume\":\"31 4\",\"pages\":\"Article 106274\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2022-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Stroke & Cerebrovascular Diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1052305721006790\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Stroke & Cerebrovascular Diseases","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1052305721006790","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Stroke is one of the primary causes of mortality and morbidity worldwide. It can be ischemic or hemorrhagic, and the former can be due to an in-situ thrombus or a distant embolus. Despite being a rare cause, stroke can also be caused in the setting of infection. Bacterial agents are the most common cause of stroke, among other infectious agents. Until the antibiotic era, rheumatic heart disease was a predisposing risk factor of infective endocarditis. VZV is the most common cause of strokes in pediatric and adult populations. Cryptococcus and Candida spp are the most common yeasts involved in CNS infections, especially in immunocompromised patients. In COVID-19 patients, ischemic strokes are more common than hemorrhagic strokes. In this review, we will discuss the most common infectious agents, with particular emphasis on COVID-19.
期刊介绍：
The Journal of Stroke & Cerebrovascular Diseases publishes original papers on basic and clinical science related to the fields of stroke and cerebrovascular diseases. The Journal also features review articles, controversies, methods and technical notes, selected case reports and other original articles of special nature. Its editorial mission is to focus on prevention and repair of cerebrovascular disease. Clinical papers emphasize medical and surgical aspects of stroke, clinical trials and design, epidemiology, stroke care delivery systems and outcomes, imaging sciences and rehabilitation of stroke. The Journal will be of special interest to specialists involved in caring for patients with cerebrovascular disease, including neurologists, neurosurgeons and cardiologists.
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