框架核酸在骨再生中的应用研究进展。

Q3 Medicine

华西口腔医学杂志 Pub Date : 2021-12-01 DOI:10.7518/hxkq.2021.06.002

Yun Feng Lin

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引用次数: 0

摘要

框架核酸(FNA)是以框架形态为特征的一组DNA纳米结构。它可以设计合理的DNA序列，遵循互补碱基配对的原则构建FNA。近年来发现的DNA纳米技术构建的FNA在骨再生领域具有很大的应用潜力。在干细胞成骨分化、骨再生、血管再生、神经调节、免疫调节、药物传递等方面发挥积极作用。本文就FNA在骨再生领域的研究进展进行综述。

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Research progress on the application of framework nucleic acid in bone regeneration.

Framework nucleic acid (FNA) is a set of DNA nanostructures characterized by the framework morphology. It can design rational DNA sequences and follow the principle of complementary base pairing to construct FNA. The recent discovery of FNA constructed by DNA nanotechnology has great application potential in the field of bone regene-ration. It plays a positive role in the osteogenic differentiation of stem cells, bone regeneration, vascular regeneration, neuromodulation, immune regulation, and drug delivery. Here, we reviewed the current study findings on FNA in the field of bone regeneration.

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来源期刊

华西口腔医学杂志 Medicine-Medicine (all)

CiteScore

0.80

自引率

0.00%

发文量

6397

期刊介绍： West China Journal of Stomatology (WCJS, pISSN 1000-1182, eISSN 2618-0456, CN 51-1169/R), published bimonthly, is a peer-reviewed Open Access journal, hosted by Sichuan university and Ministry of Education of the People's Republic of China. WCJS was established in 1983 and indexed in Medline/Pubmed, SCOPUS, EBSCO, Chemical Abstract(CA), CNKI, WANFANG Data, etc.