伏替西汀对睡眠结构的影响，用于治疗患有 Narcolepsy 和 Cataplexy 的青少年患者的合并抑郁症：病例报告。

IF 0.6 4区医学 Q4 ENDOCRINOLOGY & METABOLISM

Neuro endocrinology letters Pub Date : 2021-12-21

Zuzana Mlyncekova, Robert Vysehradsky, Ingrid Tonhajzerova, Peter Hutka, Michaela Krivosova, Andrea Hamrakova, Andrea Hamrakova, Igor Ondrejka, Karel Sonka

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引用次数: 0

摘要

本报告介绍了一例罕见的青少年患者，该患者因抑郁障碍合并 1 型嗜睡症（NT1）和新诊断的快速眼动行为障碍（RBD）而接受新型抗抑郁药物伏替西汀的治疗，并描述了病情的整体临床改善情况。此外，我们还通过评估治疗前和治疗期间的客观多导睡眠图研究，讨论了伏替西汀对睡眠结构的影响。我们认为，这种多模式血清素能药物在治疗与 NT1 相关的 RBD 方面可能具有疗效。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

本刊更多论文

Vortioxetine Effects on Sleep Architecture in Treatment of Comorbid Depression in Adolescent Patient with Narcolepsy and Cataplexy: Case Report.

This report presents a rare case of adolescent patient treated by novel antidepressant vortioxetine for depressive disorder comorbid to narcolepsy type 1 (NT1) and newly diagnosed REM behavior disorder (RBD) and describes the overall clinical improvement of the conditions. Additionally, we discuss effect of vortioxetine on sleep architecture by evaluating objective polysomnographic studies before and on the treatment. We propose a possible efficacy of this multimodal serotoninergic agent in treatment of RBD associated with NT1.

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来源期刊

Neuro endocrinology letters 医学-内分泌学与代谢

CiteScore

1.00

自引率

14.30%

发文量

审稿时长

6 months

期刊介绍： Neuroendocrinology Letters is an international, peer-reviewed interdisciplinary journal covering the fields of Neuroendocrinology, Neuroscience, Neurophysiology, Neuropsychopharmacology, Psychoneuroimmunology, Reproductive Medicine, Chronobiology, Human Ethology and related fields for RAPID publication of Original Papers, Review Articles, State-of-the-art, Clinical Reports and other contributions from all the fields covered by Neuroendocrinology Letters. Papers from both basic research (methodology, molecular and cellular biology, anatomy, histology, biology, embryology, teratology, normal and pathological physiology, biophysics, pharmacology, pathology and experimental pathology, biochemistry, neurochemistry, enzymology, chronobiology, receptor studies, endocrinology, immunology and neuroimmunology, animal physiology, animal breeding and ethology, human ethology, psychology and others) and from clinical research (neurology, psychiatry and child psychiatry, obstetrics and gynecology, pediatrics, endocrinology, immunology, cardiovascular studies, internal medicine, oncology and others) will be considered. The Journal publishes Original papers and Review Articles. Brief reports, Special Communications, proved they are based on adequate experimental evidence, Clinical Studies, Case Reports, Commentaries, Discussions, Letters to the Editor (correspondence column), Book Reviews, Congress Reports and other categories of articles (philosophy, art, social issues, medical and health policies, biomedical history, etc.) will be taken under consideration.