乳糜泻的系统方法:对主要提供者的全面回顾。

IF 1.6 Q2 MEDICINE, GENERAL & INTERNAL

Romanian Journal of Internal Medicine Pub Date : 2022-06-14 Print Date: 2022-06-01 DOI:10.2478/rjim-2022-0002

Pedro Cortés, Dana M Harris, Yan Bi

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引用次数: 2

摘要

乳糜泻是一种免疫介导的疾病，在遗传易感患者接触麸质。它的特点是小肠慢性淋巴细胞炎症导致绒毛萎缩及其相关并发症。乳糜泻的全球患病率正在上升，部分原因是筛查试验的改进和诊断标准的简化。新的治疗方法正在开发，包括蛋白水解酶、隔离剂和免疫疗法。然而，严格的无麸质饮食仍然是治疗的主要方法。在这篇全面的综述中，我们讨论了乳糜泻的流行病学、定义、诊断和治疗。

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Systematic approach to celiac disease: a comprehensive review for primary providers.

Celiac disease is an immune-mediated illness to gluten exposure in genetically susceptible patients. It is characterized by chronic lymphocytic inflammation of the small bowel leading to villous atrophy and its associated complications. The global prevalence of celiac disease is increasing, due in part to improved screening tests and simplified diagnostic criteria. Novel therapies are being developed and include proteolytic enzymes, sequestering agents, and immunotherapies. A strict gluten-free diet, however, remains the mainstay of treatment. In this comprehensive review, we discuss the epidemiology, definitions, diagnosis, and treatment of celiac disease.

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来源期刊

Romanian Journal of Internal Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

3.20

自引率

5.30%

发文量

审稿时长

15 weeks

期刊介绍： Romanian Journal of Physics is a journal publishing physics contributions on the following themes: •Theoretical Physics & Applied Mathematics •Nuclear Physics •Solid State Physics & Materials Science •Statistical Physics & Quantum Mechanics •Optics •Spectroscopy •Plasma & Lasers •Nuclear & Elementary Particles Physics •Atomic and Molecular Physics •Astrophysics •Atmosphere and Earth Science •Environment Protection