使用雌激素补充剂与囊性纤维化妇女较高的生活质量评分相关

IF 4.2 Q1 ENDOCRINOLOGY & METABOLISM
Malinda Wu , Neha Arora , Viranuj Sueblinvong , William R. Hunt , Vin Tangpricha
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引用次数: 0

摘要

雌激素补充使用与囊性纤维化(CF)妇女生活质量的关系尚不清楚。在这项横断面研究中,患有CF的女性在常规CF诊所访问期间完成了生活质量问卷。在CF问卷修订(CFQ-R)的所有领域中,雌激素补充的使用与更高的生活质量评分相关,并且在作用限制和呼吸领域中具有显著意义。大多数目前没有使用雌激素补充剂的参与者以前都使用过雌激素补充剂。大多数参与者使用雌激素来调节月经,预防怀孕和控制月经前后的症状。雌激素补充的使用与生活空间流动性或性功能障碍筛查的差异无关。这是迄今为止最大的一项研究,调查了CF女性补充雌激素与生活质量之间的关系。需要前瞻性随机研究来阐明补充雌激素与CF女性生活质量之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Use of estrogen supplementation is associated with higher quality of life scores in women with cystic fibrosis

Use of estrogen supplementation is associated with higher quality of life scores in women with cystic fibrosis

The association of estrogen supplementation use and quality of life in women with cystic fibrosis (CF) is not well characterized. In this cross-sectional study, women with CF completed quality of life questionnaires during a routine CF clinic visit. The use of estrogen supplementation was associated with higher quality of life scores in all domains of the CF questionnaire-revised (CFQ-R) and was significant in the role limitations and respiratory domains. Most participants who were not currently using estrogen supplementation had previously used estrogen supplementation. Most participants had used estrogen to regulate menses, prevent pregnancy and control symptoms around menses. Use of estrogen supplementation was not associated with differences in life-space mobility or screening for sexual dysfunction. This is the largest study to date investigating the association of estrogen supplementation and quality of life in women with CF. Prospective randomized studies are needed to clarify the association of estrogen supplementation and quality of life in women with CF.

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来源期刊
CiteScore
6.10
自引率
0.00%
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24
审稿时长
16 weeks
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