[Granulomatous skeletal lesions].

The main granulomatous diseases of the musculoskeletal system are Langerhans cell histiocytosis, sarcoidosis, Erdheim-Chester disease (lipoidgranulomatosis) and mastocytosis. In most cases the patients have only a few symptoms, and the disease is detected coincidentally. The diagnosis is usually made by a synopsis of topographical presentation, clinical appearance and the radiological pattern (destruction, reactive new bone formation).